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Sara SantaCruz-Calvo

Explore the profile of Sara SantaCruz-Calvo including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 101
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Recent Articles
1.
Kalantar G, Saraswat S, SantaCruz-Calvo S, Gholamrezaeinejad F, Javidan A, Agrawal M, et al.
Nutrients . 2024 May; 16(10. PMID: 38794641
Cytokines produced by peripheral T-helper 1/17 cells disproportionately contribute to the inflammation (i.e., metaflammation) that fuels type 2 diabetes (T2D) pathogenesis. Shifts in the nutrient milieu could influence inflammation through...
2.
Rockhold J, Marszalkowski H, Sannella M, Gibney K, Murphy L, Zukowski E, et al.
Geroscience . 2024 May; 46(6):5681-5699. PMID: 38761287
Aging is associated with the onset and progression of multiple diseases, which limit health span. Chronic low-grade inflammation in the absence of overt infection is considered the simmering source that...
3.
Zukowski E, Sannella M, Rockhold J, Kalantar G, Yu J, SantaCruz-Calvo S, et al.
Aging Cell . 2023 Oct; 22(11):e13996. PMID: 37837188
Aging promotes numerous intracellular changes in T cells that impact their effector function. Our data show that aging promotes an increase in the localization of STAT3 to the mitochondria (mitoSTAT3),...
4.
Pugh G, Fouladvand S, SantaCruz-Calvo S, Agrawal M, Zhang X, Chen J, et al.
Obesity (Silver Spring) . 2022 Sep; 30(10):1983-1994. PMID: 36069294
Objective: Myeloid cells dominate metabolic disease-associated inflammation (metaflammation) in mouse obesity, but the contributions of myeloid cells to the peripheral inflammation that fuels sequelae of human obesity are untested. This...
5.
Conway R, Rockhold J, SantaCruz-Calvo S, Zukowski E, Pugh G, Hasturk H, et al.
Front Aging . 2022 Aug; 3:924003. PMID: 35928250
Obesity promotes the onset and progression of metabolic and inflammatory diseases such as type 2 diabetes. The chronic low-grade inflammation that occurs during obesity triggers multiple signaling mechanisms that negatively...
6.
SantaCruz-Calvo S, Bharath L, Pugh G, SantaCruz-Calvo L, Lenin R, Lutshumba J, et al.
Nat Rev Endocrinol . 2021 Oct; 18(1):23-42. PMID: 34703027
Obesity and type 2 diabetes mellitus (T2DM) are increasing in prevalence owing to decreases in physical activity levels and a shift to diets that include addictive and/or high-calorie foods. These...
7.
Calvo I, SantaCruz-Calvo S, Aranzana M, Marmol P, Luque J, Peral I, et al.
Arch Bronconeumol (Engl Ed) . 2020 Sep; 56(11):761-763. PMID: 32994088
No abstract available.
8.
SantaCruz-Calvo S, SantaCruz-Calvo L, Nikolajczyk B
Immunometabolism . 2020 Apr; 2(2). PMID: 32292596
The burden of aging and obesity is urging extended investigation into the molecular mechanisms that underlie chronic adipose tissue inflammation. B cell-targeted therapies are emerging as novel tools to modulate...
9.
Siendones E, SantaCruz-Calvo S, Martin-Montalvo A, Cascajo M, Ariza J, Lopez-Lluch G, et al.
Antioxid Redox Signal . 2014 Jan; 21(12):1708-25. PMID: 24450884
Aims: Membrane-bound CYB5R3 deficiency in humans causes recessive hereditary methaemoglobinaemia (RHM), an incurable disease that is characterized by severe neurological disorders. CYB5R3 encodes for NADH-dependent redox enzyme that contributes to...