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Sara Romani

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Articles 23
Citations 234
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Recent Articles
1.
Chua J, Ntem-Mensah A, Abutaleb A, Husson J, Mutumbi L, Lam K, et al.
J Med Virol . 2020 Nov; 93(6):3752-3760. PMID: 33150966
Combination regimens of direct-acting antiviral agents (DAAs) for chronic genotype 1 hepatitis C virus (HCV) infection given for 8 or 12 weeks have high cure rates. Shortened treatment durations that...
2.
Ghosh A, Romani S, Kottilil S, Poonia B
Int J Mol Sci . 2020 Oct; 21(20). PMID: 33050486
Chronic HCV (CHC) infection is the only chronic viral infection for which curative treatments have been discovered. These direct acting antiviral (DAA) agents target specific steps in the viral replication...
3.
Kim J, Ghosh A, Ayithan N, Romani S, Khanam A, Park J, et al.
Sci Rep . 2020 Apr; 10(1):5947. PMID: 32231233
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
4.
Kim J, Ghosh A, Ayithan N, Romani S, Khanam A, Park J, et al.
Sci Rep . 2020 Feb; 10(1):1835. PMID: 32020034
Chronic hepatitis B (CHB) infection functional cure is defined as sustained loss of HBsAg and several therapeutic strategies are in clinical development designed to pharmacologically reduce serum HBsAg, break immune...
5.
Romani S, Stafford K, Nelson A, Bagchi S, Kottilil S, Poonia B
Front Immunol . 2019 Jul; 10:1470. PMID: 31316516
Direct acting antiviral (DAA) regimens of 12 weeks result in HCV clearance in vast majority of patients across genotypes. We previously demonstrated an ultra-short regimen of 4 weeks DAA cleared...
6.
Ghosh A, Mondal R, Romani S, Bagchi S, Cairo C, Pauza C, et al.
J Viral Hepat . 2019 May; 26(9):1105-1116. PMID: 31074195
Immune dysfunction is a hallmark of chronic HCV infection and viral clearance with direct antivirals recover some of these immune defects. TCRVγ9Vδ2 T-cell dysfunction in treated HCV patients however is...
7.
Shrivastava S, Bhatta M, Ward H, Romani S, Lee R, Rosenthal E, et al.
Hepatol Commun . 2018 Dec; 2(12):1451-1466. PMID: 30556035
Patients coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) have higher levels of immune activation, impaired antigen-specific responses, and accelerated fibrogenesis compared to patients monoinfected with HCV....
8.
Romani S, Hosseini S, Mohebbi S, Boonstra A, Hosseini Razavi A, Sharifian A
Gastroenterol Hepatol Bed Bench . 2018 Jun; 11(2):131-137. PMID: 29910854
Aim: To determine the distribution of important mutations of the "a" determinant region in the HBV genome among patients in different clinical phases of HBV infection. Background: Variations in Hepatitis...
9.
Kashfi S, Behboudi Farahbakhsh F, Nazemalhosseini Mojarad E, Mashayekhi K, Azimzadeh P, Romani S, et al.
Tumour Biol . 2015 Sep; 37(2):2119-26. PMID: 26346169
Gastric cancer (GC) is the second cause of cancer-related death worldwide. Interleukin (IL)-16 has a vital role in the development and homeostasis of the immune system. In the present study,...
10.
Romani S, Hosseini S, Mohebbi S, Kazemian S, Derakhshani S, Khanyaghma M, et al.
Hepat Res Treat . 2015 Feb; 2014:790753. PMID: 25692036
Host genetic background is known as an important factor in patients' susceptibility to infectious diseases such as viral hepatitis. The aim of this study was to determine the effect of...