Sara M Elkashef
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Explore the profile of Sara M Elkashef including associated specialties, affiliations and a list of published articles.
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6
Citations
98
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Recent Articles
1.
Guo X, Elkashef S, Patel A, Morais G, Shnyder S, Loadman P, et al.
Carbohydr Polym
. 2021 Mar;
259:117741.
PMID: 33674001
Polysialic acid (polySia) is a linear polysaccharide comprised of N-acetylneuraminic acid residues and its over-expression in cancer cells has been correlated with poor clinical prognosis. An assay has been developed...
2.
Qiu Z, Lin A, Jiang S, Elkashef S, Myers J, Srikantan S, et al.
Cell Chem Biol
. 2020 Feb;
27(5):538-550.e7.
PMID: 32101699
Mitochondrial D2HGDH and L2HGDH catalyze the oxidation of D-2-HG and L-2-HG, respectively, into αKG. This contributes to cellular homeostasis in part by modulating the activity of αKG-dependent dioxygenases. Signals that...
3.
Guo X, Elkashef S, Loadman P, Patterson L, Falconer R
Carbohydr Polym
. 2019 Sep;
224:115145.
PMID: 31472857
Polysialic acid (polySia) is a unique, well-characterised carbohydrate polymer highly-expressed on the cell surface of neurons in the early stages of mammalian brain development. Post-embryogenesis, it is also re-expressed in...
4.
Elkashef S, Lin A, Myers J, Sill H, Jiang D, Dahia P, et al.
Cancer Cell
. 2017 May;
31(5):619-620.
PMID: 28486104
No abstract available.
5.
Elkashef S, Allison S, Sadiq M, Basheer H, Morais G, Loadman P, et al.
Sci Rep
. 2016 Sep;
6:33026.
PMID: 27611649
Polysialic acid (polySia) is a unique carbohydrate polymer expressed on the surface of NCAM (neuronal cell adhesion molecule) in a number of cancers where it modulates cell-cell and cell-matrix adhesion,...
6.
Elkashef S, Sutherland M, Patterson L, Loadman P, Falconer R
Analyst
. 2016 Aug;
141(20):5849-5856.
PMID: 27517096
The polysialyltransferases are biologically important glycosyltransferase enzymes responsible for the biosynthesis of polysialic acid, a carbohydrate polymer that plays a critical role in the progression of several diseases, notably cancer....