Sara Ladu
Overview
Explore the profile of Sara Ladu including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
1883
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pellegrino R, Calvisi D, Neumann O, Kolluru V, Wesely J, Chen X, et al.
Hepatology
. 2013 Nov;
59(5):1886-99.
PMID: 24285179
Unlabelled: Mouse Double Minute homolog 4 (MDM4) gene up-regulation often occurs in human hepatocellular carcinoma (HCC), but the molecular mechanisms responsible for its induction remain poorly understood. Here we investigated...
2.
Tschaharganeh D, Chen X, Latzko P, Malz M, Gaida M, Felix K, et al.
Gastroenterology
. 2013 Feb;
144(7):1530-1542.e12.
PMID: 23419361
Background & Aims: Cancer cells often lose contact inhibition to undergo anchorage-independent proliferation and become resistant to apoptosis by inactivating the Hippo signaling pathway, resulting in activation of the transcriptional...
3.
Wang C, Delogu S, Ho C, Lee S, Gui B, Jiang L, et al.
J Hepatol
. 2012 May;
57(3):577-83.
PMID: 22617155
Background & Aims: Aberrant activation of the AKT oncogenic pathway and downregulation of the Sprouty 2 (Spry2) tumor suppressor gene are frequently observed molecular events in human hepatocarcinogenesis. The goal...
4.
Evert M, Calvisi D, Evert K, De Murtas V, Gasparetti G, Mattu S, et al.
Hepatology
. 2012 Jan;
55(5):1473-84.
PMID: 22271091
Unlabelled: Mounting epidemiological evidence supports a role for insulin-signaling deregulation and diabetes mellitus in human hepatocarcinogenesis. However, the underlying molecular mechanisms remain unknown. To study the oncogenic effect of chronically...
5.
Ho C, Wang C, Mattu S, Destefanis G, Ladu S, Delogu S, et al.
Hepatology
. 2011 Oct;
55(3):833-45.
PMID: 21993994
Unlabelled: Activation of v-akt murine thymoma viral oncogene homolog (AKT) and Ras pathways is often implicated in carcinogenesis. However, the oncogenic cooperation between these two cascades in relationship to hepatocellular...
6.
Calvisi D, Simile M, Ladu S, Frau M, Evert M, Tomasi M, et al.
Hepatology
. 2011 Apr;
53(4):1226-36.
PMID: 21480327
Unlabelled: Up-regulation of the v-Myb avian myeloblastosis viral oncogene homolog-like2 B-Myb (MYBL2) gene occurs in human hepatocellular carcinoma (HCC) and is associated with faster progression of rodent hepatocarcinogenesis. We evaluated,...
7.
Frau M, Ladu S, Calvisi D, Simile M, Bonelli P, Daino L, et al.
J Hepatol
. 2011 Mar;
55(1):111-9.
PMID: 21419759
Background & Aims: MYBL2 is implicated in human malignancies and over expressed in hepatocellular carcinoma (HCC). We investigated Mybl2 role in the acquisition of susceptibility to HCC and tumor progression....
8.
Calvisi D, Wang C, Ho C, Ladu S, Lee S, Mattu S, et al.
Gastroenterology
. 2010 Dec;
140(3):1071-83.
PMID: 21147110
Background & Aims: De novo lipogenesis is believed to be involved in oncogenesis. We investigated the role of aberrant lipid biosynthesis in the pathogenesis of human hepatocellular carcinoma (HCC). Methods:...
9.
Calvisi D, Ladu S, Conner E, Seo D, Hsieh J, Factor V, et al.
J Hepatol
. 2010 Nov;
54(2):311-9.
PMID: 21067840
Background & Aims: Aberrant activation of the RAS pathway is ubiquitous in human hepatocarcinogenesis, but the molecular mechanisms leading to RAS induction in the absence of RAS mutations remain under-investigated....
10.
Lee S, Ladu S, Evert M, Dombrowski F, De Murtas V, Chen X, et al.
Hepatology
. 2010 Aug;
52(2):506-17.
PMID: 20683950
Unlabelled: Sprouty2 (Spry2), a negative feedback regulator of the Ras/mitogen-activated protein kinase (MAPK) pathway, is frequently down-regulated in human hepatocellular carcinoma (HCC). We tested the hypothesis that loss of Spry2...