Sara Keeble
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Explore the profile of Sara Keeble including associated specialties, affiliations and a list of published articles.
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14
Citations
187
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Recent Articles
1.
Hunnicutt K, Callahan C, Callahan C, Keeble S, Moore E, Good J, et al.
Genetics
. 2024 Nov;
229(2).
PMID: 39601270
Hybrid incompatibilities are a critical component of species barriers and may arise due to negative interactions between divergent regulatory elements in parental species. We used a comparative approach to identify...
2.
Hunnicutt K, Callahan C, Keeble S, Moore E, Good J, Larson E
bioRxiv
. 2023 Nov;
PMID: 37961317
Hybrid incompatibilities are a critical component of species barriers and may arise due to negative interactions between divergent regulatory elements in parental species. We used a comparative approach to identify...
3.
Larson E, Kopania E, Hunnicutt K, Vanderpool D, Keeble S, Good J
G3 (Bethesda)
. 2022 Feb;
12(3).
PMID: 35134904
No abstract available.
4.
Kopania E, Larson E, Callahan C, Keeble S, Good J
Mol Biol Evol
. 2022 Jan;
39(2).
PMID: 35099536
Genes involved in spermatogenesis tend to evolve rapidly, but we lack a clear understanding of how protein sequences and patterns of gene expression evolve across this complex developmental process. We...
5.
Beckman E, Martins F, Suzuki T, Bi K, Keeble S, Good J, et al.
Genetics
. 2021 Dec;
220(2).
PMID: 34897431
Understanding the genetic basis of environmental adaptation in natural populations is a central goal in evolutionary biology. The conditions at high elevation, particularly the low oxygen available in the ambient...
6.
Larson E, Kopania E, Hunnicutt K, Vanderpool D, Keeble S, Good J
G3 (Bethesda)
. 2021 Dec;
12(2).
PMID: 34864964
Hybrid sterility is a complex phenotype that can result from the breakdown of spermatogenesis at multiple developmental stages. Here, we disentangle two proposed hybrid male sterility mechanisms in the house...
7.
Keeble S, Firman R, Sarver B, Clark N, Simmons L, Dean M
Biol Reprod
. 2021 May;
105(4):1043-1055.
PMID: 34007991
Studies of fertilization biology often focus on sperm and egg interactions. However, before gametes interact, mammalian sperm must pass through the cumulus layer; in mice, this consists of several thousand...
8.
Sarver B, Pennell M, Brown J, Keeble S, Hardwick K, Sullivan J, et al.
PeerJ
. 2019 Mar;
7:e6334.
PMID: 30886768
Comparative methods allow researchers to make inferences about evolutionary processes and patterns from phylogenetic trees. In Bayesian phylogenetics, estimating a phylogeny requires specifying priors on parameters characterizing the branching process...
9.
Larson E, Vanderpool D, Sarver B, Callahan C, Keeble S, Provencio L, et al.
Genetics
. 2018 Apr;
209(3):845-859.
PMID: 29692350
Resolving the mechanistic and genetic bases of reproductive barriers between species is essential to understanding the evolutionary forces that shape speciation. Intrinsic hybrid incompatibilities are often treated as fixed between...
10.
Chang P, Kopania E, Keeble S, Sarver B, Larson E, Orth A, et al.
Mamm Genome
. 2017 Aug;
28(9-10):416-425.
PMID: 28819774
The house mouse is a powerful model to dissect the genetic basis of phenotypic variation, and serves as a model to study human diseases. Despite a wealth of discoveries, most...