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Sara E Patterson

Explore the profile of Sara E Patterson including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 1156
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Recent Articles
1.
Gredler M, Patterson S, Seifert A, Cohn M
Dev Biol . 2020 Jul; 465(1):23-30. PMID: 32645357
Congenital anomalies of external genitalia affect approximately 1 in 125 live male births. Development of the genital tubercle, the precursor of the penis and clitoris, is regulated by the urethral...
2.
Hill D, Harper A, Malcolm J, McAndrews M, Mockus S, Patterson S, et al.
BMC Cancer . 2019 Nov; 19(1):1039. PMID: 31684899
Background: Understanding mechanisms underlying specific chemotherapeutic responses in subtypes of cancer may improve identification of treatment strategies most likely to benefit particular patients. For example, triple-negative breast cancer (TNBC) patients...
3.
Meir S, Philosoph-Hadas S, Riov J, Tucker M, Patterson S, Roberts J
J Exp Bot . 2019 Feb; 70(5):1461-1467. PMID: 30726930
Abscission is a developmental process with important implications for agricultural practices. Ethylene has long been considered as a key regulator of the abscission process. The existence of an ethylene-independent abscission...
4.
Patterson S, Statz C, Yin T, Mockus S
NPJ Precis Oncol . 2019 Jan; 3:2. PMID: 30675517
Cancer genomic data is continually growing in complexity, necessitating improved methods for data capture and analysis. Tumors often contain multiple therapeutically relevant alterations, and co-occurring alterations may have a different...
5.
Statz C, Patterson S, Mockus S
Expert Rev Mol Diagn . 2017 Apr; 17(6):549-555. PMID: 28402162
Comprehensive cancer genomic profiling provides the opportunity to expose the various molecular aberrations potentially driving tumor progression. Consequently, the identity of these genetic drivers can be utilized to match a...
6.
Statz C, Patterson S, Mockus S
Target Oncol . 2016 Aug; 12(1):47-59. PMID: 27503005
Background: The progression of prostate cancer to castration-resistant prostate cancer (CRPC) is often a result of somatic alterations in the PI3K/Akt/mTOR (mammalian target of rapamycin) pathway, suggesting that therapies targeting...
7.
Patterson S, Bolivar-Medina J, Falbel T, Hedtcke J, Nevarez-McBride D, Maule A, et al.
Front Plant Sci . 2016 Feb; 6:1268. PMID: 26858730
As the world population grows and resources and climate conditions change, crop improvement continues to be one of the most important challenges for agriculturalists. The yield and quality of many...
8.
Tafe L, Muller K, Ananda G, Mitchell T, Spotlow V, Patterson S, et al.
Am J Pathol . 2016 Jan; 186(3):671-7. PMID: 26797085
Benign ovarian Brenner tumors often are associated with mucinous cystic neoplasms, which are hypothesized to share a histogenic origin and progression, however, supporting molecular characterization is limited. Our goal was...
9.
Patterson S, Liu R, Statz C, Durkin D, Lakshminarayana A, Mockus S
Hum Genomics . 2016 Jan; 10:4. PMID: 26772741
Background: Precision medicine in oncology relies on rapid associations between patient-specific variations and targeted therapeutic efficacy. Due to the advancement of genomic analysis, a vast literature characterizing cancer-associated molecular aberrations...
10.
Mockus S, Patterson S, Statz C, Bult C, Tsongalis G
Clin Chem . 2015 Nov; 62(3):442-8. PMID: 26607725
Background: Availability of genomic information used in the management of cancer treatment has outpaced both regulatory and reimbursement efforts. Many types of clinical trials are underway to validate the utility...