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Sara Del Mare

Explore the profile of Sara Del Mare including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 490
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Recent Articles
1.
Nishri Y, Vatarescu M, Luz I, Epstein L, Dumancic M, Del Mare S, et al.
Front Oncol . 2022 Oct; 12:888100. PMID: 36237307
Glioblastoma multiforme (GBM) is at present an incurable disease with a 5-year survival rate of 5.5%, despite improvements in treatment modalities such as surgery, radiation therapy, chemotherapy [e.g., temozolomide (TMZ)],...
2.
Del Mare S, Nishri Y, Shai A, Efrati M, Deutsch L, Den R, et al.
Int J Radiat Oncol Biol Phys . 2022 Aug; 115(3):707-718. PMID: 36031029
Purpose: Diffusing alpha-emitters Radiation Therapy (DaRT) releases alpha-emitting atoms into the tumor microenvironment. The treatment effectively ablates human and mice xenografts and shows 100% response rates in skin or head...
3.
Del Mare S, Husanie H, Iancu O, Abu-Odeh M, Evangelou K, Lovat F, et al.
Cancer Res . 2016 Aug; 76(20):6107-6117. PMID: 27550453
Osteosarcoma is a highly metastatic form of bone cancer in adolescents and young adults that is resistant to existing treatments. Development of an effective therapy has been hindered by very...
4.
Del Mare S, Aqeilan R
Sci Rep . 2015 Aug; 5:12959. PMID: 26256646
Osteosarcoma (OS) is among the most frequently occurring primary bone tumors, primarily affecting adolescents and young adults. This malignant osteoid forming tumor is characterized by its metastatic potential, mainly to...
5.
Abdeen S, Del Mare S, Hussain S, Abu-Remaileh M, Salah Z, Hagan J, et al.
J Cell Physiol . 2012 Dec; 228(7):1377-82. PMID: 23254685
WW domain-containing oxidoreductase (WWOX) is highly conserved in both human and murine. WWOX spans the second most common human chromosomal fragile site, FRA16D, and is commonly inactivated in multiple human...
6.
Jones K, Salah Z, Del Mare S, Galasso M, Gaudio E, Nuovo G, et al.
Cancer Res . 2012 Feb; 72(7):1865-77. PMID: 22350417
Osteosarcoma remains a leading cause of cancer death in adolescents. Treatment paradigms and survival rates have not improved in two decades. Driving the lack of therapeutic inroads, the molecular etiology...
7.
Del Mare S, Kurek K, Stein G, Lian J, Aqeilan R
Am J Cancer Res . 2011 Jul; 1(5):585-94. PMID: 21731849
Osteosarcoma is the most common primary bone malignancy in children with unknown etiology and often with poor clinical outcome. In recent years, a critical role has emerged for the WW...
8.
Kurek K, Del Mare S, Salah Z, Abdeen S, Sadiq H, Lee S, et al.
Cancer Res . 2010 Jun; 70(13):5577-86. PMID: 20530675
The WW domain-containing oxidoreductase (WWOX) is a tumor suppressor that is deleted or attenuated in most human tumors. Wwox-deficient mice develop osteosarcoma (OS), an aggressive bone tumor with poor prognosis...
9.
Cecconi V, Moro M, Del Mare S, Sidney J, Bachi A, Longhi R, et al.
Eur J Immunol . 2010 Mar; 40(6):1603-16. PMID: 20306469
Detection of CD4(+) T cells specific for tumor-associated antigens is critical to investigate the spontaneous tumor immunosurveillance and to monitor immunotherapy protocols in patients. We investigated the ability of HLA-DR...
10.
Del Mare S, Salah Z, Aqeilan R
J Cell Biochem . 2009 Aug; 108(4):737-45. PMID: 19708029
The WW domain-containing oxidoreductase (WWOX) spans one of the most active common fragile sites (CFSs) involved in cancer, FRA16D. WWOX encodes a 46-kDa protein that contains two N-terminal WW domains...