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Sara Caylor

Explore the profile of Sara Caylor including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 204
Followers 0
Related Specialties
Genetics
Pharmacology
Health Services
Top 10 Co-Authors
Stephen F Kingsmore
Sergey Batalov
Yan Ding
David Dimmock
Narayanan Veeraraghavan
Kristen Wigby
Katarzyna Ellsworth
Erica Sanford
Annette Feigenbaum
Gunter Scharer
Published In
Am J Hum Genet
NPJ Genom Med
Clin Ther
Children (Basel)
Affiliations
Soon will be listed here.
Recent Articles
1.
Genome-based newborn screening for severe childhood genetic diseases has high positive predictive value and sensitivity in a NICU pilot trial
Kingsmore S, Wright M, Olsen L, Schultz B, Protopsaltis L, Averbuj D, et al.
Am J Hum Genet . 2024 Dec; 111(12):2643-2667. PMID: 39642868
Large prospective clinical trials are underway or planned that examine the clinical utility and cost effectiveness of genome-based newborn screening (gNBS). One gNBS platform, BeginNGS, currently screens 53,575 variants for...
2.
Prequalification of genome-based newborn screening for severe childhood genetic diseases through federated training based on purifying hyperselection
Kingsmore S, Wright M, Smith L, Liang Y, Mowrey W, Protopsaltis L, et al.
Am J Hum Genet . 2024 Dec; 111(12):2618-2642. PMID: 39642867
Genome-sequence-based newborn screening (gNBS) has substantial potential to improve outcomes in hundreds of severe childhood genetic disorders (SCGDs). However, a major impediment to gNBS is imprecision due to variants classified...
3.
Assessing Diversity in Newborn Genomic Sequencing Research Recruitment: Race/Ethnicity and Primary Spoken Language Variation in Eligibility, Enrollment, and Reasons for Declining
Cakici J, Dimmock D, Caylor S, Gaughran M, Clarke C, Triplett C, et al.
Clin Ther . 2023 Jul; 45(8):736-744. PMID: 37429778
Purpose: Diagnostic genomic research has the potential to directly benefit participants. This study sought to identify barriers to equitable enrollment of acutely ill newborns into a diagnostic genomic sequencing research...
4.
Response to Grosse et al
Kingsmore S, Smith L, Kunard C, Bainbridge M, Batalov S, Benson W, et al.
Am J Hum Genet . 2023 Jun; 110(6):1017. PMID: 37267897
No abstract available.
5.
Breaking Barriers to Rapid Whole Genome Sequencing in Pediatrics: Michigan's Project Baby Deer
Bupp C, Ames E, Arenchild M, Caylor S, Dimmock D, Fakhoury J, et al.
Children (Basel) . 2023 Jan; 10(1). PMID: 36670656
The integration of precision medicine in the care of hospitalized children is ever evolving. However, access to new genomic diagnostics such as rapid whole genome sequencing (rWGS) is hindered by...
6.
A genome sequencing system for universal newborn screening, diagnosis, and precision medicine for severe genetic diseases
Kingsmore S, Smith L, Kunard C, Bainbridge M, Batalov S, Benson W, et al.
Am J Hum Genet . 2022 Aug; 109(9):1605-1619. PMID: 36007526
Newborn screening (NBS) dramatically improves outcomes in severe childhood disorders by treatment before symptom onset. In many genetic diseases, however, outcomes remain poor because NBS has lagged behind drug development....
7.
Project Baby Bear: Rapid precision care incorporating rWGS in 5 California children's hospitals demonstrates improved clinical outcomes and reduced costs of care
Dimmock D, Caylor S, Waldman B, Benson W, Ashburner C, Carmichael J, et al.
Am J Hum Genet . 2021 Jun; 108(7):1231-1238. PMID: 34089648
Genetic disorders are a leading contributor to mortality in neonatal and pediatric intensive care units (ICUs). Rapid whole-genome sequencing (rWGS)-based rapid precision medicine (RPM) is an intervention that has demonstrated...
8.
Author Correction: Rapid whole genome sequencing impacts care and resource utilization in infants with congenital heart disease
Sweeney N, Nahas S, Chowdhury S, Batalov S, Clark M, Caylor S, et al.
NPJ Genom Med . 2021 May; 6(1):38. PMID: 34039997
No abstract available.
9.
Publisher Correction: Rapid whole genome sequencing impacts care and resource utilization in infants with congenital heart disease
Sweeney N, Nahas S, Chowdhury S, Batalov S, Clark M, Caylor S, et al.
NPJ Genom Med . 2021 May; 6(1):39. PMID: 34039980
No abstract available.
10.
Rapid whole genome sequencing impacts care and resource utilization in infants with congenital heart disease
Sweeney N, Nahas S, Chowdhury S, Batalov S, Clark M, Caylor S, et al.
NPJ Genom Med . 2021 Apr; 6(1):29. PMID: 33888711
Congenital heart disease (CHD) is the most common congenital anomaly and a major cause of infant morbidity and mortality. While morbidity and mortality are highest in infants with underlying genetic...