Sara B Mulinyawe
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Explore the profile of Sara B Mulinyawe including associated specialties, affiliations and a list of published articles.
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11
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2504
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Recent Articles
1.
Geraghty A, Acosta-Alvarez L, Rotiroti M, Dutton S, ODea M, Woo P, et al.
bioRxiv
. 2024 May;
PMID: 38798554
Persistent central nervous system (CNS) immune dysregulation and consequent dysfunction of multiple neural cell types is central to the neurobiological underpinnings of a cognitive impairment syndrome that can occur following...
2.
Zhang T, Bhambri A, Zhang Y, Barbosa D, Bae H, Xue J, et al.
Cell Rep
. 2023 Aug;
42(8):112943.
PMID: 37543947
Oligodendrocytes are the sole myelin-producing cells in the central nervous system. Oligodendrocyte number is tightly controlled across diverse brain regions to match local axon type and number, yet the underlying...
3.
Zhang T, Bae H, Bhambri A, Zhang Y, Barbosa D, Xue J, et al.
bioRxiv
. 2023 Jan;
PMID: 36712125
Highlights: Autophagy flux increases in the premyelinating and myelinating oligodendrocytesAutophagy promotes premyelinating oligodendrocyte (pre-OL) apoptosis to control myelination location and timing Autophagy acts in the TFEB-PUMA-Bax/Bak pathway and elevates mRNA...
4.
Pan Y, Hysinger J, Barron T, Schindler N, Cobb O, Guo X, et al.
Nature
. 2021 May;
594(7862):277-282.
PMID: 34040258
Neurons have recently emerged as essential cellular constituents of the tumour microenvironment, and their activity has been shown to increase the growth of a diverse number of solid tumours. Although...
5.
Floriddia E, Lourenco T, Zhang S, van Bruggen D, Hilscher M, Kukanja P, et al.
Nat Commun
. 2020 Nov;
11(1):5860.
PMID: 33203872
Mature oligodendrocytes (MOLs) show transcriptional heterogeneity, the functional consequences of which are unclear. MOL heterogeneity might correlate with the local environment or their interactions with different neuron types. Here, we...
6.
Sun L, Mulinyawe S, Collins H, Ibrahim A, Li Q, Simon D, et al.
Cell
. 2018 Dec;
175(7):1811-1826.e21.
PMID: 30503207
Nervous system function depends on proper myelination for insulation and critical trophic support for axons. Myelination is tightly regulated spatially and temporally, but how it is controlled molecularly remains largely...
7.
Bennett F, Bennett M, Yaqoob F, Mulinyawe S, Grant G, Hayden Gephart M, et al.
Neuron
. 2018 Jun;
98(6):1170-1183.e8.
PMID: 29861285
Microglia, the brain's resident macrophages, are dynamic CNS custodians with surprising origins in the extra-embryonic yolk sac. The consequences of their distinct ontogeny are unknown but critical to understanding and...
8.
Bohlen C, Bennett F, Tucker A, Collins H, Mulinyawe S, Barres B
Neuron
. 2017 May;
94(4):759-773.e8.
PMID: 28521131
Microglia, the resident macrophages of the CNS, engage in various CNS-specific functions that are critical for development and health. To better study microglia and the properties that distinguish them from...
9.
Bennett M, Bennett F, Liddelow S, Ajami B, Zamanian J, Fernhoff N, et al.
Proc Natl Acad Sci U S A
. 2016 Feb;
113(12):E1738-46.
PMID: 26884166
The specific function of microglia, the tissue resident macrophages of the brain and spinal cord, has been difficult to ascertain because of a lack of tools to distinguish microglia from...
10.
Eroglu C, Allen N, Susman M, ORourke N, Park C, Ozkan E, et al.
Cell
. 2009 Oct;
139(2):380-92.
PMID: 19818485
Synapses are asymmetric cellular adhesions that are critical for nervous system development and function, but the mechanisms that induce their formation are not well understood. We have previously identified thrombospondin...