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Santosh L Saraf

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Articles 104
Citations 1011
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Recent Articles
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Sinha U, Setty S, Pilon C, Brown J, Ruiz M, Ren G, et al.
Br J Haematol . 2025 Jan; PMID: 39748216
We describe a patient with sickle cell disease (SCD) and elevated antiphospholipid antibodies (aPL) who developed multi-organ failure resembling catastrophic antiphospholipid syndrome. Autoimmune screening revealed several autoantibodies characteristic of systemic...
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OBrien J, Jonassaint C, Parchuri E, Lalama C, Badawy S, Hamm M, et al.
J Pain . 2024 Oct; 26:104720. PMID: 39447944
Painimation, a novel digital pain assessment tool, allows patients to communicate their pain quality, intensity, and location using abstract animations (painimations) and a paintable body image. This study determined the...
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Jonassaint C, Lalama C, Carroll C, Badawy S, Hamm M, Stinson J, et al.
Blood Adv . 2024 Oct; 8(24):6257-6266. PMID: 39374587
Despite the burden of chronic pain in sickle cell disease (SCD), nonpharmacological approaches remain limited. This multisite, randomized trial compared digital cognitive behavioral therapy (CBT) with a digital pain/SCD education...
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Han J, Zhang X, Shah B, Saraf S, Gordeuk V
Br J Haematol . 2024 May; 205(2):716-718. PMID: 38772687
No abstract available.
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Ruiz M, Zhang X, Mansilla M, Zahr R, Thomas C, Smith R, et al.
Br J Haematol . 2024 May; 205(1):316-319. PMID: 38735682
The pathophysiology and genetic risk for sickle cell disease (SCD)-related chronic kidney disease (CKD) are not well understood. In 70 adults with SCD-related CKD and without APOL1 inherited in a...
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Jain D, Gupta M, Madkaikar M, Jena R, Khargekar N, Saraf S, et al.
Lancet Haematol . 2024 May; 11(5):e322-e323. PMID: 38701819
No abstract available.
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Zahr R, Rashkin S, Ruiz M, Elsherif L, Ren G, Salas G, et al.
Haematologica . 2024 May; 109(10):3368-3372. PMID: 38695132
No abstract available.
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Sun R, Srivastava A, Derebail V, Han J, Molokie R, Gordeuk V, et al.
Am J Hematol . 2024 Apr; 99(8):1610-1612. PMID: 38655752
No abstract available.
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Saraf S, Hagar R, Idowu M, Osunkwo I, Cruz K, Kuypers F, et al.
Blood Adv . 2024 Apr; 8(16):4459-4475. PMID: 38640200
Etavopivat is an investigational, once daily, oral, selective erythrocyte pyruvate kinase (PKR) activator. A multicenter, randomized, placebo-controlled, double-blind, 3-part, phase 1 study was conducted to characterize the safety and clinical...