Santosh L Gaonkar
Overview
Explore the profile of Santosh L Gaonkar including associated specialties, affiliations and a list of published articles.
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11
Citations
50
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0
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Recent Articles
1.
Siddappa T, Ravish A, Xi Z, Mohan A, Girimanchanaika S, Krishnamurthy N, et al.
ACS Omega
. 2025 Jan;
10(1):114-126.
PMID: 39829533
STAT3 has emerged as a validated target in cancer, being functionally associated with breast cancer (BC) development, growth, resistance to chemotherapy, metastasis, and evasion of immune surveillance. Previously, a series...
2.
Dwarakanath D, Nayak Y, Kulal A, Pandey S, Pai K, Gaonkar S
Sci Rep
. 2024 Dec;
14(1):31994.
PMID: 39738776
This study explores the design, synthesis, and evaluation of a novel series of isobenzofuran-based imidazo[2,1-b][1,3,4]thiadiazole derivatives, targeting their antimicrobial and anticancer properties. These compounds integrate the pharmacologically significant 1,3,4-thiadiazole and...
3.
Sanjai C, Gaonkar S, Hakkimane S
ACS Omega
. 2024 Nov;
9(43):43302-43318.
PMID: 39494011
The vast diversity of plants in nature offers a rich reservoir of bioactive compounds that have historically played an integral role in pharmacotherapy and continue to serve as a primary...
4.
Sanjai C, Hakkimane S, Guru B, Gaonkar S
Bioorg Chem
. 2023 Nov;
142:106973.
PMID: 37984104
The development of effective anticancer strategies and the improvement of our understanding of cancer need analytical tools. Utilizing a variety of analytical approaches while investigating anti-cancer medicines gives us a...
5.
P P, G A, Mishma J, Sinha R, Suvarna A, Gaonkar S
Heliyon
. 2023 Nov;
9(10):e21014.
PMID: 37916072
6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole. HCl (FPBH), a substituted benzisoxazole derivative, was prepared from isonipecotic acid and characterized using various spectroscopic techniques. Using electrochemical examinations such as potentiodynamic polarisation (PDP) and electrochemical impedance spectroscopic...
6.
Ravish A, Narasimhachar B, Xi Z, Vishwanath D, Mohan A, Gaonkar S, et al.
Biomedicines
. 2023 Oct;
11(10).
PMID: 37893090
Nuclear factor kappa B (NF-κB) is a potential therapeutic target in breast cancer. In the current study, a new class of oxazine- and piperazine-linked pyrimidines was developed as inhibitors of...
7.
Vishwanath D, Xi Z, Ravish A, Mohan A, Basappa S, Krishnamurthy N, et al.
Molecules
. 2023 Jul;
28(13).
PMID: 37446915
Histone deacetylases (HDACs) are an attractive drug target for the treatment of human breast cancer (BC), and therefore, HDAC inhibitors (HDACis) are being used in preclinical and clinical studies. The...
8.
Manjunath R, Gaonkar S, Musad Saleh E, Husain K
Saudi J Biol Sci
. 2022 Jul;
29(9):103372.
PMID: 35855306
The world has been combating different variants of SARS-COV-19 since its first outbreak in Wuhan city. SARS-COV-19 is caused by the coronavirus. The corona virus mutates and becomes more transmissible...
9.
Nayak S, Gaonkar S, Hazra D, Chawla K, Hari G, Pai K, et al.
Chem Biodivers
. 2022 Mar;
19(5):e202100956.
PMID: 35304823
In drug discovery, the hybridization of bioactive pharmacophores is a powerful tool for targeting enzymes involved in cancer and microbial cell growth. A combination of 1,3,4-oxadiazole and isobenzofuran may improve...
10.
Nayak S, Gaonkar S
ChemMedChem
. 2020 Dec;
16(9):1360-1390.
PMID: 33277791
New weapons are constantly needed in the fight against cancer. The discovery of cisplatin as an anticancer drug prompted the search for new metal complexes. The successful history of cisplatin...