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Sanjiv Sam Gambhir

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Articles 181
Citations 7111
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Recent Articles
11.
Sachindra S, Hellberg T, Exner S, Prasad S, Beindorff N, Rogalla S, et al.
Front Oncol . 2021 Jun; 11:684713. PMID: 34136410
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignant neoplasms, as many cases go undetected until they reach an advanced stage. Integrin αvβ6 is a cell surface...
12.
Chen Y, Zhao Y, Beinat C, Zlitni A, Hsu E, Chen D, et al.
Nat Nanotechnol . 2021 Mar; 16(6):717-724. PMID: 33782588
Molecular imaging is a crucial technique in clinical diagnostics but it relies on radioactive tracers or strong magnetic fields that are unsuitable for many patients, particularly infants and pregnant women....
13.
Steinberg I, Kim J, Schneider M, Hyun D, Zlitni A, Hopper S, et al.
IEEE Trans Med Imaging . 2021 Mar; 40(7):1888-1897. PMID: 33755561
Photoacoustic (PA) imaging can revolutionize medical ultrasound by augmenting it with molecular information. However, clinical translation of PA imaging remains a challenge due to the limited viewing angles and imaging...
14.
Avanzini S, Kurtz D, Chabon J, Moding E, Hori S, Gambhir S, et al.
Sci Adv . 2020 Dec; 6(50). PMID: 33310847
Early cancer detection aims to find tumors before they progress to an incurable stage. To determine the potential of circulating tumor DNA (ctDNA) for cancer detection, we developed a mathematical...
15.
Cui L, Gouw A, LaGory E, Guo S, Attarwala N, Tang Y, et al.
Nat Biotechnol . 2020 Oct; 39(3):357-367. PMID: 33077961
Depletion of mitochondrial copper, which shifts metabolism from respiration to glycolysis and reduces energy production, is known to be effective against cancer types that depend on oxidative phosphorylation. However, existing...
16.
Fuchigami T, Haywood T, Gowrishankar G, Anders D, Namavari M, Wardak M, et al.
Mol Imaging Biol . 2020 Jul; 22(5):1151-1160. PMID: 32691392
Purpose: [F]FHBG has been used as a positron emission tomography (PET) imaging tracer for the monitoring of herpes simplex virus type 1 thymidine kinase (HSV1-tk), a reporter gene for cell...
17.
Jung K, Kim T, Yu J, Rhee S, Zhao W, Ha B, et al.
Nat Biomed Eng . 2020 Jun; 4(8):835-844. PMID: 32541917
In vivo molecular imaging can measure the average kinetics and movement routes of injected cells through the body. However, owing to non-specific accumulation of the contrast agent and its efflux...
18.
Wardak M, Gowrishankar G, Zhao X, Liu Y, Chang E, Namavari M, et al.
Circulation . 2020 May; 141(21):1729-1731. PMID: 32453662
No abstract available.
19.
Zlitni A, Gowrishankar G, Steinberg I, Haywood T, Gambhir S
Nat Commun . 2020 Mar; 11(1):1250. PMID: 32144257
Currently, there are no non-invasive tools to accurately diagnose wound and surgical site infections before they become systemic or cause significant anatomical damage. Fluorescence and photoacoustic imaging are cost-effective imaging...
20.
Song G, Kenney M, Chen Y, Zheng X, Deng Y, Chen Z, et al.
Nat Biomed Eng . 2020 Feb; 4(3):325-334. PMID: 32015409
The low magnetic saturation of iron oxide nanoparticles, which are developed primarily as contrast agents for magnetic resonance imaging, limits the sensitivity of their detection using magnetic particle imaging (MPI)....