Sangdun Choi
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Explore the profile of Sangdun Choi including associated specialties, affiliations and a list of published articles.
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178
Citations
4495
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Recent Articles
1.
Ahn M, Choi Y, Lee S, Choi S, Kim H
Eur J Immunol
. 2025 Feb;
55(2):e202451227.
PMID: 39931754
The inflammatory response triggered by Toll-like receptors (TLRs) may implicated in the development of the pathogenesis of adult-onset Still's disease (AOSD). This study evaluated the efficacy of TLR inhibitor peptides,...
2.
Farooq M, Hwang M, Hwang M, Khan A, Batool M, Ahmad B, et al.
Life Sci
. 2025 Jan;
364:123432.
PMID: 39884341
Aims: Fibroblast growth factor (FGF) is a broad class of secretory chemicals that act via FGF receptors (FGFR). The study aims to explore the role of a novel peptide, FAP1...
3.
Farooq M, Ahmad B, Han J, Patra M, Khan A, Choi H, et al.
Biomed Pharmacother
. 2025 Jan;
183:117801.
PMID: 39756124
Myeloid differentiation primary-response 88 (MyD88) is a crucial adaptor protein for initiating immune responses via Toll-like receptors (TLRs). This study employed a rational peptide design approach to develop MyD88 inhibitory...
4.
Pirzada R, Yasmeen F, Haseeb M, Javaid N, Kim E, Choi S
Int J Biol Macromol
. 2024 Nov;
282(Pt 5):137295.
PMID: 39515709
The human interleukin-1 receptor I (IL-1R1) is a cytokine receptor recognized by interleukin 1β (IL-1β), among other cytokines. Over activation of IL-1R1 has been implicated in various inflammatory conditions. This...
5.
Yasmeen F, Pirzada R, Ahmad B, Choi B, Choi S
Int J Mol Sci
. 2024 Jul;
25(14).
PMID: 39062908
Autoimmunity refers to an organism's immune response against its own healthy cells, tissues, or components, potentially leading to irreversible damage to vital organs. Central and peripheral tolerance mechanisms play crucial...
6.
Javaid N, Ahmad B, Patra M, Choi S
FEBS J
. 2024 Jul;
291(19):4372-4391.
PMID: 39003565
Tumor necrosis factor (TNF) is a pro-inflammatory cytokine and its functional homotrimeric form interacts with the TNF receptor (TNFR) to activate downstream apoptotic, necroptotic, and inflammatory signaling pathways. Excessive activation...
7.
Ramachandran R, Manan A, Kim J, Choi S
Exp Mol Med
. 2024 Jun;
56(7):1488-1500.
PMID: 38945951
Proinflammatory cytokines and chemokines play a crucial role in regulating the inflammatory response, which is essential for the proper functioning of our immune system. When infections or threats to the...
8.
Kim J, Kim J, Byeon H, Kim J, Kim H, Suh C, et al.
Int J Mol Sci
. 2024 Jun;
25(12).
PMID: 38928513
Arterial macrophage cholesterol accumulation and impaired cholesterol efflux lead to foam cell formation and the development of atherosclerosis. Modified lipoproteins interact with toll-like receptors (TLR), causing an increased inflammatory response...
9.
Lee S, Choi S, Kim M
J Control Release
. 2024 Jun;
372:467-481.
PMID: 38917954
Rheumatoid arthritis (RA) is an autoimmune disease characterized by systemic inflammation that primarily affects joint tissue and requires frequent medication. Recently, we developed cyclic phage-display-derived inhibitory peptides (CPs), which act...
10.
Haseeb M, Choi Y, Patra M, Jeong U, Lee W, Qayyum N, et al.
J Chem Inf Model
. 2024 Jun;
64(13):5090-5107.
PMID: 38904299
The aberrant secretion of proinflammatory cytokines by immune cells is the principal cause of inflammatory diseases, such as systemic lupus erythematosus and rheumatoid arthritis. Toll-like receptor 7 (TLR7) and TLR9,...