Sandro R Valentini
Overview
Explore the profile of Sandro R Valentini including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
797
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Recent Articles
1.
Mazzeu B, Souza-Moreira T, Oliveira A, Remlinger M, Felippe L, Valentini S, et al.
Molecules
. 2021 Nov;
26(22).
PMID: 34833897
Friedelin, a pentacyclic triterpene found in the leaves of the Celastraceae species, demonstrates numerous biological activities and is a precursor of quinonemethide triterpenes, which are promising antitumoral agents. Friedelin is...
2.
Meneguello L, Barbosa N, Pereira K, Proenca A, Tamborlin L, Simabuco F, et al.
J Cell Biochem
. 2018 Oct;
120(4):6015-6025.
PMID: 30320934
Ribosomal S6 kinase 1 (S6K1) and S6K2 proteins are effectors of the mammalian target of rapamycin complex 1 pathway, which control the process of protein synthesis in eukaryotes. S6K2 is...
3.
Souza-Moreira T, Navarrete C, Chen X, Zanelli C, Valentini S, Furlan M, et al.
FEMS Yeast Res
. 2018 Apr;
18(5).
PMID: 29617770
A complexity of pathway expression in yeast compared to prokaryotes is the need for separate promoters and terminators for each gene expressed. Single transcript expression and separated protein production is...
4.
Alves T, Souza-Moreira T, Valentini S, Zanelli C, Furlan M
Molecules
. 2018 Mar;
23(3).
PMID: 29558378
Triterpenes are interesting compounds because they play an important role in cell homeostasis and a wide variety exhibiting defense functions is produced by plant secondary metabolism. Those same plant secondary...
5.
Souza-Moreira T, Alves T, Pinheiro K, Felippe L, de Lima G, Watanabe T, et al.
Sci Rep
. 2016 Nov;
6:36858.
PMID: 27874020
Among the biologically active triterpenes, friedelin has the most-rearranged structure produced by the oxidosqualene cyclases and is the only one containing a cetonic group. In this study, we cloned and...
6.
Barbosa N, Boldrin P, Rossi D, Yamamoto P, Watanabe T, Serrao V, et al.
Amino Acids
. 2016 Jul;
48(10):2363-74.
PMID: 27388480
The translation elongation factor eIF5A is conserved through evolution and is necessary to rescue the ribosome during translation elongation of polyproline-containing proteins. Although the site of eIF5A binding to the...
7.
Rossi D, Barbosa N, Galvao F, Boldrin P, Hershey J, Zanelli C, et al.
PLoS One
. 2016 Apr;
11(4):e0154205.
PMID: 27115996
eIF5A is the only protein known to contain the essential and unique amino acid residue hypusine. eIF5A functions in both translation initiation due to its stimulation of methionyl-puromycin synthesis and...
8.
Morais A, Terzian A, Duarte D, Bronzoni R, Madrid M, Gavioli A, et al.
Virol J
. 2013 Jun;
10:205.
PMID: 23800076
Background: Yellow fever virus (YFV) belongs to the Flavivirus genus and causes an important disease. An alarming resurgence of viral circulation and the expansion of YFV-endemic zones have been detected...
9.
Leao R, Cruz F, Carneiro-de-Oliveira P, Rossetto D, Valentini S, Zanelli C, et al.
Pharmacol Biochem Behav
. 2013 Jan;
104:169-76.
PMID: 23333681
We investigated the behavioral and molecular interactions between cocaine and nicotine, through evaluating locomotor activity, nicotine intravenous self-administration and gene expression. Locomotor sensitization was induced in male Wistar rats by...
10.
Tanaka M, Giro E, Cavalcante L, Pires J, Apponi L, Valentini S, et al.
Cytokine
. 2012 Sep;
60(3):875-81.
PMID: 22995210
Background: Recently, attenuation of anti-inflammatory and increase of pro-inflammatory mediators was demonstrated in individuals with Down syndrome (DS) in comparison with euploid patients during periodontal disease (PD), suggesting a shift...