Sandrine Chabas
Overview
Explore the profile of Sandrine Chabas including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
894
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0
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Recent Articles
1.
Korkut D, Alves I, Vogel A, Chabas S, Sharma C, Martinez D, et al.
Biochim Biophys Acta Gen Subj
. 2019 Sep;
1864(1):129423.
PMID: 31476357
Background: We previously reported the identification of the aapA1/IsoA1 locus as part of a new family of toxin-antitoxin (TA) systems in the human pathogen Helicobacter pylori. AapA1 belongs to type...
2.
Masachis S, Tourasse N, Lays C, Faucher M, Chabas S, Iost I, et al.
Elife
. 2019 Aug;
8.
PMID: 31411564
Post-transcriptional regulation plays important roles to fine-tune gene expression in bacteria. In particular, regulation of type I toxin-antitoxin (TA) systems is achieved through sophisticated mechanisms involving toxin mRNA folding. Here,...
3.
Iost I, Chabas S, Darfeuille F
Nucleic Acids Res
. 2019 Apr;
47(11):5906-5921.
PMID: 31006803
In most bacteria, ribosomal RNA is transcribed as a single polycistronic precursor that is first processed by RNase III. This double-stranded specific RNase cleaves two large stems flanking the 23S...
4.
Masachis S, Tourasse N, Chabas S, Bouchez O, Darfeuille F
Methods Enzymol
. 2018 Dec;
612:67-100.
PMID: 30502958
As the number of bacterial genomes and transcriptomes increases, so does the number of newly identified toxin-antitoxin (TA) systems. However, their functional characterization remains challenging, often requiring the use of...
5.
Arnion H, Korkut D, Masachis Gelo S, Chabas S, Reignier J, Iost I, et al.
Nucleic Acids Res
. 2017 Jan;
45(8):4782-4795.
PMID: 28077560
Type I toxin-antitoxin (TA) systems have been identified in a wide range of bacterial genomes. Here, we report the characterization of a new type I TA system present on the...
6.
Baud J, Varon C, Chabas S, Chambonnier L, Darfeuille F, Staedel C
PLoS One
. 2013 Apr;
8(4):e60315.
PMID: 23565224
Chronic Helicobacter pylori infection provokes an inflammation of the gastric mucosa, at high risk for ulcer and cancer development. The most virulent strains harbor the cag pathogenicity island (cagPAI) encoding...
7.
Belair C, Baud J, Chabas S, Sharma C, Vogel J, Staedel C, et al.
Silence
. 2011 Oct;
2(1):7.
PMID: 22027184
Background: MicroRNAs, post-transcriptional regulators of eukaryotic gene expression, are implicated in host defense against pathogens. Viruses and bacteria have evolved strategies that suppress microRNA functions, resulting in a sustainable infection....
8.
Jalvy-Delvaille S, Maurel M, Majo V, Pierre N, Chabas S, Combe C, et al.
Nucleic Acids Res
. 2011 Oct;
40(3):1356-65.
PMID: 22009679
Besides the fact that miR-96 and miR-182 belong to the miR-182/183 cluster, their seed region (UUGGCA, nucleotides 2-7) is identical suggesting potential common properties in mRNA target recognition and cellular...
9.
Sharma C, Hoffmann S, Darfeuille F, Reignier J, Findeiss S, Sittka A, et al.
Nature
. 2010 Feb;
464(7286):250-5.
PMID: 20164839
Genome sequencing of Helicobacter pylori has revealed the potential proteins and genetic diversity of this prevalent human pathogen, yet little is known about its transcriptional organization and noncoding RNA output....
10.
Jaffrelo L, Chabas S, Reigadas S, Pflieger A, Wychowski C, Rumi J, et al.
Nucleic Acids Res
. 2008 Jul;
36(15):e95.
PMID: 18614605
We developed a functional selection system based on randomized genetic elements (GE) to identify potential regulators of hepatitis C virus (HCV) RNA translation, a process initiated by an internal ribosomal...