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Sandra Spurr-Michaud

Explore the profile of Sandra Spurr-Michaud including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 972
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Recent Articles
1.
Arafat S, Robert M, Abud T, Spurr-Michaud S, Amparo F, Dohlman C, et al.
Am J Ophthalmol . 2017 Jan; 176:46-52. PMID: 28073648
Purpose: To investigate the levels of neutrophil elastase (NE), matrix metalloproteinases (MMPs), and myeloperoxidase (MPO) in tear washes of patients with ocular graft-vs-host disease (oGVHD). Design: Case-control study. Methods: Based...
2.
Menon B, Zhou X, Spurr-Michaud S, Rajaiya J, Chodosh J, Gipson I
mSphere . 2016 Jun; 1(1). PMID: 27303700
Human adenoviruses (HAdV), species D in particular (HAdV-D), are frequently associated with epidemic keratoconjunctivitis (EKC). Although the infection originates at the ocular surface epithelium, the mechanisms by which HAdV-Ds bypass...
3.
Robert M, Arafat S, Spurr-Michaud S, Chodosh J, Dohlman C, Gipson I
Cornea . 2016 May; 35(7):1008-14. PMID: 27191670
Purpose: To investigate the tear levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO), and tissue inhibitor of metalloproteinase-1 in eyes after Boston keratoprosthesis type I (B-KPro) implantation and to correlate these...
4.
Gipson I, Spurr-Michaud S, Tisdale A
Exp Eye Res . 2016 Jan; 145:230-234. PMID: 26731719
MUC16 is an extraordinarily large 22,152 amino acid membrane spanning mucin that has been shown to be present in the glycocalyx of the apical cells of the human cornea and...
5.
Robert M, Spurr-Michaud S, Frenette M, Young D, Gipson I, Dohlman C
Int J Pharm Compd . 2015 Jan; 18(5):418-26. PMID: 25577892
The purpose of this study was to develop a novel 10-mg/mL infliximab eye drop, to characterize its physical and biological stability under recommended storage conditions, and to assess the formulation's...
6.
Gipson I, Spurr-Michaud S, Tisdale A, Menon B
PLoS One . 2014 Jun; 9(6):e100393. PMID: 24968021
Membrane-anchored mucins are present in the apical surface glycocalyx of mucosal epithelial cells, each mucosal epithelium having at least two of the mucins. The mucins have been ascribed barrier functions,...
7.
Marko C, Tisdale A, Spurr-Michaud S, Evans C, Gipson I
Invest Ophthalmol Vis Sci . 2013 Dec; 55(1):291-300. PMID: 24327612
Purpose: Recent development of mice null for either Muc5ac or Muc5b mucin allows study of their specific roles at the mouse ocular surface. A recent report indicated that Muc5ac null...
8.
Arafat S, Suelves A, Spurr-Michaud S, Chodosh J, Foster C, Dohlman C, et al.
Ophthalmology . 2013 Aug; 121(1):79-87. PMID: 23962653
Objective: To investigate the levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO), and tissue inhibitor of metalloproteinase-1 (TIMP-1) in tears of patients with Stevens-Johnson syndrome (SJS) and ocular cicatricial pemphigoid (OCP)....
9.
Paschalis E, Chodosh J, Spurr-Michaud S, Cruzat A, Tauber A, Behlau I, et al.
Invest Ophthalmol Vis Sci . 2013 May; 54(6):3863-73. PMID: 23661373
Purpose: Recent use of a titanium (Ti) backplate has improved the design and biocompatibility of the Boston Keratoprosthesis (BKpro). Titanium's shiny metallic appearance, however, makes the cosmetic outcome less favorable....
10.
Govindarajan B, Menon B, Spurr-Michaud S, Rastogi K, Gilmore M, Argueso P, et al.
PLoS One . 2012 Mar; 7(3):e32418. PMID: 22412870
The majority of bacterial infections occur across wet-surfaced mucosal epithelia, including those that cover the eye, respiratory tract, gastrointestinal tract and genitourinary tract. The apical surface of all these mucosal...