Sandra Jimenez-Gancedo
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Explore the profile of Sandra Jimenez-Gancedo including associated specialties, affiliations and a list of published articles.
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7
Citations
177
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Recent Articles
1.
Fernandez-Ayala D, Jimenez-Gancedo S, Guerra I, Hernandez-Camacho J, Neto M, Scialo F, et al.
Free Radic Biol Med
. 2025 Jan;
230:95-111.
PMID: 39864756
The interference of the expression of each of the genes involved in the synthesis of coenzyme Q (CoQ) in Drosophila melanogaster can help to understand the pathophysiology of CoQ-dependent mitochondrial...
2.
Moreno-Onate M, Gallardo-Fuentes L, Martinez-Garcia P, Naranjo S, Jimenez-Gancedo S, Tena J, et al.
Nucleic Acids Res
. 2024 Feb;
52(7):3682-3701.
PMID: 38321954
Retinoic acid (RA) is the ligand of RA receptors (RARs), transcription factors that bind to RA response elements. RA signaling is required for multiple processes during embryonic development, including body...
3.
Gil-Galvez A, Jimenez-Gancedo S, Perez-Posada A, Franke M, Acemel R, Lin C, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(11):e2114802119.
PMID: 35263228
SignificanceIn this manuscript, we address an essential question in developmental and evolutionary biology: How have changes in gene regulatory networks contributed to the invertebrate-to-vertebrate transition? To address this issue, we...
4.
Gerrard D, Berry A, Jennings R, Birket M, Zarrineh P, Garstang M, et al.
Nat Commun
. 2020 Aug;
11(1):3920.
PMID: 32764605
How the genome activates or silences transcriptional programmes governs organ formation. Little is known in human embryos undermining our ability to benchmark the fidelity of stem cell differentiation or cell...
5.
Magri M, Jimenez-Gancedo S, Bertrand S, Madgwick A, Escriva H, Lemaire P, et al.
Front Cell Dev Biol
. 2020 Feb;
7:372.
PMID: 32039199
-regulatory elements (CREs) are non-coding DNA regions involved in the spatio-temporal regulation of gene expression. Gene regulatory changes drive animal development and play major roles during evolution of animal body...
6.
Marletaz F, Firbas P, Maeso I, Tena J, Bogdanovic O, Perry M, et al.
Nature
. 2018 Nov;
564(7734):64-70.
PMID: 30464347
Vertebrates have greatly elaborated the basic chordate body plan and evolved highly distinctive genomes that have been sculpted by two whole-genome duplications. Here we sequence the genome of the Mediterranean...
7.
Fernandez-Ayala D, Jimenez-Gancedo S, Guerra I, Navas P
Mol Syndromol
. 2014 Aug;
5(3-4):170-9.
PMID: 25126050
The human syndrome of coenzyme Q (CoQ) deficiency is a heterogeneous mitochondrial disease characterized by a diminution of CoQ content in cells and tissues that affects all the electron transport...
8.
Fernandez-Ayala D, Guerra I, Jimenez-Gancedo S, Cascajo M, Gavilan A, DiMauro S, et al.
BMJ Open
. 2013 Mar;
3(3).
PMID: 23533218
Objectives: Coenzyme Q10 (CoQ10) deficiency syndrome is a rare condition that causes mitochondrial dysfunction and includes a variety of clinical presentations as encephalomyopathy, ataxia and renal failure. First, we sought...