Sandra J Shefelbine
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Explore the profile of Sandra J Shefelbine including associated specialties, affiliations and a list of published articles.
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94
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2108
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Recent Articles
1.
Meslier Q, Hoffmann J, Oehrlein R, Kurczy D, Monaghan J, Shefelbine S
Bone
. 2025 Feb;
193:117422.
PMID: 39978613
Bones adapt to external mechanical loads through a process known as mechanoadaptation. Osteocytes are the bone cells that sense the mechanical environment and initiate a biological response. Investigating the changes...
2.
Meslier Q, Duerr T, Guan W, Nguyen B, Monaghan J, Shefelbine S
FASEB J
. 2024 Oct;
38(19):e70101.
PMID: 39387181
Bone is a three-dimensional (3D) highly dynamic tissue under constant remodeling. Commonly used tools to investigate bone biology require sample digestion for biomolecule extraction or provide only two-dimensional (2D) spatial...
3.
Kondiboyina V, Boyer T, Mooney N, Bajpayee A, Shefelbine S
J Biomech
. 2024 Aug;
174:112265.
PMID: 39137485
Chondrocytes respond to mechanical stimuli by increasing their intracellular calcium concentration. The response depends on the cellular environment. Previous studies have investigated chondrocytes under slow strain rates or cells embedded...
4.
Young L, Munro E, Somanchi P, Bemis A, Smith S, Shefelbine S
Anat Rec (Hoboken)
. 2024 Jun;
307(11):3506-3518.
PMID: 38850161
We compare the effects of burrowing behavior on appendicular bone structure in two Peromyscus (deer mouse) species. P. polionotus creates complex burrows in their territories, while P. eremicus is a...
5.
Lewis C, Shefelbine S
J Orthop Res
. 2024 Apr;
42(9):2054-2060.
PMID: 38644357
Altered shape of the proximal femur (cam morphology) or acetabulum (pincer morphology) is indicative of femoroacetabular impingement, which can result in hip pain and osteoarthritis of the hip. As mechanical...
6.
Kondiboyina V, Duerr T, Monaghan J, Shefelbine S
J Mech Behav Biomed Mater
. 2023 Dec;
150:106341.
PMID: 38160643
Background: The extracellular mechanical environment plays an important role in the skeletal development process. Characterization of the material properties of regenerating tissues that recapitulate development, provides insights into the mechanical...
7.
Astrologo A, Nano S, Klemm E, Shefelbine S, Dennerlein J
Appl Ergon
. 2023 Dec;
116:104183.
PMID: 38071785
This study aimed to determine gravitational and dynamic torques and muscle activity of the neck across a series of design parameters of head mounted displays (mass, center of mass, and...
8.
Morgan M, Farra Y, Vergara-Anglim A, Bellini C, Oakes J, Shefelbine S
J Biomech
. 2023 Dec;
162:111879.
PMID: 38043496
Numerous studies have shown the detrimental health effects of tobacco smoking on bone volume and strength in human and animal models. Little is known regarding the impacts of e-cigarettes, a...
9.
Ryan N, Shefelbine S, Shapiro F
MethodsX
. 2023 Nov;
11:102428.
PMID: 37954966
Lamellar bone formed in individuals with moderate and severe osteogenesis imperfecta (OI) is often composed of lamellae that are structurally abnormal. Measuring the thickness of these lamellae can be helpful...
10.
Sadeghian S, Arthurs O, Li X, Lewis C, Shefelbine S
HSS J
. 2023 Nov;
19(4):418-427.
PMID: 37937091
Background: Abnormal prenatal hip joint loading can lead to compromised hip joint function. Early intervention is crucial for favorable outcomes. Purpose: This study investigates the impact of treatment timing (initiation...