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Sandosh Padmanabhan

Explore the profile of Sandosh Padmanabhan including associated specialties, affiliations and a list of published articles. Areas
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Articles 251
Citations 12816
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Recent Articles
1.
Walker H, Khan S, Padmanabhan S, Pell J, Lewsey J, Mackay D, et al.
BMC Nephrol . 2025 Mar; 26(1):113. PMID: 40038631
Background: NICE guidelines recommend GPs use the kidney failure risk equation (KFRE) to identify people with chronic kidney disease (CKD) at higher risk of kidney failure. Albuminuria results are required...
2.
Le N, Tran T, McClure J, Gill D, Padmanabhan S
Eur Heart J Cardiovasc Pharmacother . 2025 Feb; PMID: 39963705
Aims: Emerging antihypertensive drug classes offer new opportunities to manage hypertension, however, their long-term effects on cardiovascular, kidney and metabolic (CKM) outcomes remain to be elucidated. This study aims to...
3.
Mair F, Nickpour F, Nicholl B, Macdonald S, Joyce D, Cooper J, et al.
J Multimorb Comorb . 2024 Oct; 14:26335565241272682. PMID: 39364424
Background: The number of individuals living with multiple (≥2) long term conditions (MLTCs) is a growing global challenge. People with MLTCs experience reduced life expectancy, complex healthcare needs, higher healthcare...
4.
Willems S, Ng N, Fernandez J, Fine R, Wheeler E, Wessel J, et al.
Wellcome Open Res . 2024 Sep; 8():483. PMID: 39280063
Background: Genome-wide association studies for glycemic traits have identified hundreds of loci associated with these biomarkers of glucose homeostasis. Despite this success, the challenge remains to link variant associations to...
5.
Zhou M, Mary S, Delles C, Padmanabhan S, Graham D, McBride M, et al.
Curr Hypertens Rep . 2024 Sep; 26(12):497-504. PMID: 39259220
Purpose Of Review: We review the role of uromodulin, a protein exclusively expressed in the kidney, in blood pressure regulation and hypertension. Recent Findings: The last few years have seen...
6.
Morrow A, Young R, Abraham G, Hoole S, Greenwood J, Arnold J, et al.
Circulation . 2024 Sep; 150(21):1671-1683. PMID: 39217504
Background: Microvascular angina is associated with dysregulation of the endothelin system and impairments in myocardial blood flow, exercise capacity, and health-related quality of life. The G allele of the noncoding...
7.
Young W, van der Most P, Bartz T, Bos M, Biino G, Duong T, et al.
J Am Heart Assoc . 2024 Aug; 13(17):e034760. PMID: 39206732
Background: Ventricular repolarization time (ECG QT and JT intervals) is associated with malignant arrhythmia. Genome-wide association studies have identified 230 independent loci for QT and JT; however, 50% of their...
8.
McCallum L, Lip S, McConnachie A, Brooksbank K, MacIntyre I, Doney A, et al.
Hypertension . 2024 Jul; 81(10):2049-2059. PMID: 39077768
Background: UMOD (uromodulin) has been linked to hypertension through potential activation of Na-K-2Cl cotransporter (NKCC2), a target of loop diuretics. We posited that hypertensive patients carrying the rs13333226-AA genotype would...
9.
Tran T, Lip S, Du Toit C, Kalaria T, Bhaskar R, ONeil A, et al.
CJC Open . 2024 Jul; 6(6):798-804. PMID: 39022171
Background: Inaccurate blood pressure (BP) classification results in inappropriate treatment. We tested whether machine learning (ML), using routine clinical data, can serve as a reliable alternative to ambulatory BP monitoring...
10.
Canning J, Strawbridge R, Miedzybrodzka Z, Marioni R, Melbye M, Porteous D, et al.
Crit Rev Clin Lab Sci . 2024 Jun; 61(8):685-708. PMID: 38855982
This scoping review aimed to synthesize the analytical techniques used and methodological limitations encountered when undertaking secondary research using residual neonatal dried blood spot (DBS) samples. Studies that used residual...