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Sandi L Navarro

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Articles 48
Citations 643
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Recent Articles
1.
Prentice R, Aragaki A, Zheng C, Manson J, Tinker L, Schoeller D, et al.
Am J Clin Nutr . 2025 Mar; PMID: 40088973
Background: Associations of the macronutrient composition of the diet with total energy intake (EI) are uncertain, as are associations of macronutrient composition with self-reported energy underreporting. Objectives: We aim to...
2.
Navarro S, Williamson B, Huang Y, Gowda G, Raftery D, Tinker L, et al.
Metabolites . 2024 Aug; 14(8). PMID: 39195559
Metabolomics has been used extensively to capture the exposome. We investigated whether prospectively measured metabolites provided predictive power beyond well-established risk factors among 758 women with adjudicated cancers [ =...
3.
Navarro S, Pinto N, Hawkins D, Park J, Dilmaghani S, Rimorin C, et al.
Cancer Chemother Pharmacol . 2024 Jul; 94(4):627-633. PMID: 39080017
Purpose: 4-hydroxycyclophosphamide (4HCY) is the principal precursor to the cytotoxic metabolite of cyclophosphamide (CY), which is often used as first-line treatment of children with cancer. There is conflicting data regarding...
4.
McCune J, Navarro S, Risler L, Phillips B, Ren S, Schoch H, et al.
Clin Transl Sci . 2023 Sep; 16(12):2577-2590. PMID: 37749994
Busulfan is hepatically metabolized through glutathione (GSH) conjugation; in vitro, this process depletes hepatocyte GSH stores and generates the cytotoxic metabolite γ-glutamyldehydroalanylglycine, which is too unstable to be quantitated in...
5.
Prentice R, Vasan S, Tinker L, Neuhouser M, Navarro S, Raftery D, et al.
J Nutr . 2023 May; 153(9):2651-2662. PMID: 37245660
Background: The Women's Health Initiative (WHI) randomized, controlled Dietary Modification (DM) trial of a low-fat dietary pattern suggested intervention benefits related to breast cancer, coronary heart disease (CHD), and diabetes....
6.
Prentice R, Vasan S, Tinker L, Neuhouser M, Navarro S, Raftery D, et al.
J Nutr . 2023 May; 153(9):2663-2677. PMID: 37178978
Background: A substantial observational literature relating specific fatty acid classes to chronic disease risk may be limited by its reliance on self-reported dietary data. Objectives: We aimed to develop biomarkers...
7.
Hanson A, Banks W, Bettcher L, Pepin R, Raftery D, Navarro S, et al.
Metabolites . 2023 Apr; 13(4). PMID: 37110227
Brain glucose hypometabolism is an early sign of Alzheimer's disease (AD), and interventions which offset this deficit, such as ketogenic diets, show promise as AD therapeutics. Conversely, high-fat feeding may...
8.
Navarro S, Gowda G, Bettcher L, Pepin R, Nguyen N, Ellenberger M, et al.
Metabolites . 2023 Apr; 13(4). PMID: 37110172
Demographic and clinical factors influence the metabolome. The discovery and validation of disease biomarkers are often challenged by potential confounding effects from such factors. To address this challenge, we investigated...
9.
Bhimani J, OConnell K, Kuk D, Du M, Navarro S, Kantor E
J Integr Complement Med . 2023 Mar; 29(8):492-500. PMID: 36971848
Glucosamine and chondroitin are supplements that are often, but not always, used in combination for arthritis and joint pain. Multiple studies have suggested that glucosamine and chondroitin may be associated...
10.
Brasky T, Ray R, Newton A, Navarro S, Schenk J, Loomans-Kropp H, et al.
Nutr Cancer . 2023 Mar; 75(4):1103-1108. PMID: 36895169
B-vitamins contribute to DNA synthesis, maintenance, and regulation. Few studies have examined associations of supplemental sources of B-vitamins with the incidence of upper gastrointestinal (GI) cancers [including gastric (GCA) and...