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Sandhya Payankaulam

Explore the profile of Sandhya Payankaulam including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 106
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Recent Articles
1.
Payankaulam S, Hickey S, Arnosti D
Cells Dev . 2021 Sep; 169:203747. PMID: 34583062
Specification of cellular polarity is vital to normal tissue development and function. Pioneering studies in Drosophila and C. elegans have elucidated the composition and dynamics of protein complexes critical for...
2.
Payankaulam S, Raicu A, Arnosti D
Genes (Basel) . 2019 Dec; 10(12). PMID: 31795422
The insulin receptor gene encodes an evolutionarily conserved signaling protein with a wide spectrum of functions in metazoan development. The insulin signaling pathway plays key roles in processes such as...
3.
Payankaulam S, Yeung K, McNeill H, Henry R, Arnosti D
Sci Rep . 2016 Mar; 6:22879. PMID: 26971715
In addition to their canonical roles in the cell cycle, RB family proteins regulate numerous developmental pathways, although the mechanisms remain obscure. We found that Drosophila Rbf1 associates with genes...
4.
Elenbaas J, Mouawad R, Henry R, Arnosti D, Payankaulam S
Cell Cycle . 2014 Dec; 14(4):589-97. PMID: 25496208
The RB tumor suppressor, a regulator of the cell cycle, apoptosis, senescence, and differentiation, is frequently mutated in human cancers. We recently described an evolutionarily conserved C-terminal "instability element" (IE)...
5.
Payankaulam S, Li L, Arnosti D
Curr Biol . 2010 Sep; 20(17):R764-71. PMID: 20833321
The regulation of gene expression by transcriptional repression is an ancient and conserved mechanism that manifests itself in diverse ways. Here we summarize conserved pathways for transcriptional repression prevalent throughout...
6.
Payankaulam S, Arnosti D
Proc Natl Acad Sci U S A . 2009 Oct; 106(41):17314-9. PMID: 19805071
Despite the pervasive roles for repressors in transcriptional control, the range of action of these proteins on cis regulatory elements remains poorly understood. Knirps has essential roles in patterning the...
7.
Payankaulam S, Arnosti D
Curr Biol . 2008 Aug; 18(15):R653-R655. PMID: 18682204
Quantitative measurements of the Hunchback transcription factor in Drosophila embryos show that its target genes can respond with a high degree of precision to the exact level of the protein,...
8.
Birmingham N, Payankaulam S, Thanesvorakul S, Stefura B, Hayglass K, Gangur V
J Immunol Methods . 2003 Apr; 275(1-2):89-98. PMID: 12667673
Passive cutaneous anaphylaxis (PCA) assay has been a gold standard method to measure allergen-specific IgE antibody (ASIgE Ab) levels in allergy mouse models. Many factors including stringent guidelines for laboratory...