Sandhitsu R Das
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Explore the profile of Sandhitsu R Das including associated specialties, affiliations and a list of published articles.
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94
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3398
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Recent Articles
1.
Sadeghpour N, Lim S, Wuestefeld A, Denning A, Ittyerah R, Trotman W, et al.
bioRxiv
. 2025 Feb;
PMID: 39990318
Background: The anterior portion of the medial temporal lobe (MTL) is one of the first regions targeted by pathology in sporadic Alzheimer's disease (AD) and Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)...
2.
Xie L, Das S, Li Y, Wisse L, McGrew E, Lyu X, et al.
Alzheimers Dement
. 2025 Jan;
21(2):e14492.
PMID: 39868491
Introduction: The generalizability of neuroimaging and cognitive biomarkers in their sensitivity to detect preclinical Alzheimer's disease (AD) and power to predict progression in large, multisite cohorts remains unclear. Method: Longitudinal...
3.
Brown C, Das S, Cousins K, Tropea T, Plotkin A, Detre J, et al.
medRxiv
. 2025 Jan;
PMID: 39867392
Tau exhibits change in both spatial extent and density of pathology along the Alzheimer's disease (AD) spectrum with each aspect contributing to the overall burden of pathological tau. Nevertheless, studies...
4.
Chen C, Das S, Tisdall M, Hu F, Chen A, Yushkevich P, et al.
Hum Brain Mapp
. 2024 Dec;
45(18):e70082.
PMID: 39697130
In neuroimaging research, volumetric data contribute valuable information for understanding brain changes during both healthy aging and pathological processes. Extracting these measures from images requires segmenting the regions of interest...
5.
Cohen J, Phillips J, Das S, Olm C, Radhakrishnan H, Rhodes E, et al.
Neuroimage Clin
. 2024 Dec;
45:103714.
PMID: 39675237
Background: Lewy body disorders (LBD), encompassing Parkinson disease (PD), PD dementia (PDD), and dementia with Lewy bodies (DLB), are characterized by alpha-synuclein pathology but often are accompanied by Alzheimer's disease...
6.
Hrybouski S, Das S, Xie L, Brown C, Flamporis M, Lane J, et al.
medRxiv
. 2024 Nov;
PMID: 39574853
Alzheimer's disease (AD) is characterized by a long preclinical stage during which molecular markers of amyloid beta and tau pathology rise, but there is minimal neurodegeneration or cognitive decline. Previous...
7.
Duong M, Das S, Khandelwal P, Lyu X, Xie L, McGrew E, et al.
Brain
. 2024 Nov;
PMID: 39573823
Polypathology is a major driver of heterogeneity in clinical presentation and extent of neurodegeneration (N) in patients with Alzheimer Disease (AD). Beyond amyloid (A) and tau (T) pathologies, over half...
8.
Schwarz C, Choe M, Rossi S, Das S, Ittyerah R, Fletcher E, et al.
Alzheimers Dement
. 2024 Oct;
20(11):8048-8061.
PMID: 39392215
Introduction: Recent technological advances have increased the risk that de-identified brain images could be re-identified from face imagery. The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a leading source of publicly...
9.
Khandelwal P, Duong M, Sadaghiani S, Lim S, Denning A, Chung E, et al.
Imaging Neurosci (Camb)
. 2024 Sep;
2():1-30.
PMID: 39301426
MRI allows brain anatomy to be examined at high resolution and to link pathology measures with morphometric measurements. However, automated segmentation methods for brain mapping in postmortem MRI are not...
10.
Yushkevich P, Ittyerah R, Li Y, Denning A, Sadeghpour N, Lim S, et al.
Alzheimers Dement
. 2024 Sep;
20(11):8113-8128.
PMID: 39279366
This paper for the 20th anniversary of the Alzheimer's Disease Neuroimaging Initiative (ADNI) provides an overview of magnetic resonance imaging (MRI) of medial temporal lobe (MTL) subregions in ADNI using...