Sanae Furukawa
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Explore the profile of Sanae Furukawa including associated specialties, affiliations and a list of published articles.
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13
Citations
510
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Recent Articles
1.
Jaroentomeechai T, Karlsson R, Goerdeler F, Teoh F, Gronset M, de Wit D, et al.
Nat Commun
. 2024 Nov;
15(1):9668.
PMID: 39516489
Access to defined glycans and glycoconjugates is pivotal for discovery, dissection, and harnessing of a range of biological functions orchestrated by cellular glycosylation processes and the glycome. We previously employed...
2.
Konstantinidi A, Nason R, Caval T, Sun L, Sorensen D, Furukawa S, et al.
J Biol Chem
. 2022 Mar;
298(4):101784.
PMID: 35247390
Mucins and glycoproteins with mucin-like regions contain densely O-glycosylated domains often found in tandem repeat (TR) sequences. These O-glycodomains have traditionally been difficult to characterize because of their resistance to...
3.
Nason R, Bull C, Konstantinidi A, Sun L, Ye Z, Halim A, et al.
Nat Commun
. 2021 Jul;
12(1):4070.
PMID: 34210959
Mucins are a large family of heavily O-glycosylated proteins that cover all mucosal surfaces and constitute the major macromolecules in most body fluids. Mucins are primarily defined by their variable...
4.
Bull C, Nason R, Sun L, Van Coillie J, Sorensen D, Moons S, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(17).
PMID: 33893239
Siglecs are a family of sialic acid-binding receptors expressed by cells of the immune system and a few other cell types capable of modulating immune cell functions upon recognition of...
5.
Narimatsu Y, Joshi H, Nason R, Van Coillie J, Karlsson R, Sun L, et al.
Mol Cell
. 2019 Jun;
75(2):394-407.e5.
PMID: 31227230
The structural diversity of glycans on cells-the glycome-is vast and complex to decipher. Glycan arrays display oligosaccharides and are used to report glycan hapten binding epitopes. Glycan arrays are limited...
6.
Narimatsu Y, Joshi H, Yang Z, Gomes C, Chen Y, Lorenzetti F, et al.
Glycobiology
. 2018 Jan;
28(5):295-305.
PMID: 29315387
Over 200 glycosyltransferases are involved in the orchestration of the biosynthesis of the human glycome, which is comprised of all glycan structures found on different glycoconjugates in cells. The glycome...
7.
Kubota T, Kumagai A, Ito H, Furukawa S, Someya Y, Takeda N, et al.
J Virol
. 2012 Aug;
86(20):11138-50.
PMID: 22855491
Noroviruses (NoVs) bind to histo-blood group antigens, namely, ABH antigens and Lewis antigens. We previously showed the NoVs GI/2, GI/3, GI/4, and GI/8 were able to strongly bind to Lewis...
8.
Narimatsu Y, Kubota T, Furukawa S, Shimojima M, Iwasaki H, Tozawa Y, et al.
FEBS Lett
. 2011 Apr;
585(9):1276-80.
PMID: 21496458
The core 1 structure of the mucin type O-glycan is synthesized by core 1 β1,3-galactosyltransferase (C1GalT). Core 1 synthase specific molecular chaperone (Cosmc), a molecular chaperone specific for C1GalT, is...
9.
Narimatsu Y, Kubota T, Furukawa S, Morii H, Narimatsu H, Yamasaki K
J Am Chem Soc
. 2010 Apr;
132(16):5548-9.
PMID: 20355726
The hinge region of human immunoglobulin A1 (IgA1), connecting the Fab and Fc regions, is mostly composed of Ser, Thr, and Pro (VPSTPPTPSPSTPPTPSPS); hinge peptide (HP). O-Glycans are naturally attached...
10.
Kubota T, Shiba T, Sugioka S, Furukawa S, Sawaki H, Kato R, et al.
J Mol Biol
. 2006 May;
359(3):708-27.
PMID: 16650853
Mucin-type O-glycans are important carbohydrate chains involved in differentiation and malignant transformation. Biosynthesis of the O-glycan is initiated by the transfer of N-acetylgalactosamine (GalNAc) which is catalyzed by UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases...