Samuel Tahk
Overview
Explore the profile of Samuel Tahk including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
428
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0
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Recent Articles
1.
Liu B, Tahk S, Yee K, Yang R, Yang Y, Mackie R, et al.
PLoS One
. 2014 Mar;
9(2):e89464.
PMID: 24586797
Epigenetic gene silencing by histone modifications and DNA methylation is essential for cancer development. The molecular mechanism that promotes selective epigenetic changes during tumorigenesis is not understood. We report here...
2.
Liu B, Yee K, Tahk S, Mackie R, Hsu C, Shuai K
EMBO J
. 2013 Dec;
33(2):101-13.
PMID: 24357619
The selective and temporal DNA methylation plays an important role in the self-renewal and differentiation of hematopoietic stem cells (HSCs), but the molecular mechanism that controls the dynamics of DNA...
3.
Liu B, Tahk S, Yee K, Fan G, Shuai K
Science
. 2010 Oct;
330(6003):521-5.
PMID: 20966256
CD4(+)Foxp3(+) regulatory T (T(reg)) cells are important for maintaining immune tolerance. Understanding the molecular mechanism that regulates T(reg) differentiation will facilitate the development of effective therapeutic strategies against autoimmune diseases....
4.
Dawlaty M, Malureanu L, Jeganathan K, Kao E, Sustmann C, Tahk S, et al.
Cell
. 2008 Apr;
133(1):103-15.
PMID: 18394993
RanBP2 is a nucleoporin with SUMO E3 ligase activity that functions in both nucleocytoplasmic transport and mitosis. However, the biological relevance of RanBP2 and the in vivo targets of its...
5.
Tahk S, Liu B, Chernishof V, Wong K, Wu H, Shuai K
Proc Natl Acad Sci U S A
. 2007 Jul;
104(28):11643-8.
PMID: 17606919
NF-kappaB and STATs regulate multiple cellular processes through the transcriptional activation of genes with diversified functions. Although the molecular mechanisms that can turn on/off the overall NF-kappaB/STAT signaling have been...
6.
Liu B, Yang Y, Chernishof V, Ogorzalek Loo R, Jang H, Tahk S, et al.
Cell
. 2007 Jun;
129(5):903-14.
PMID: 17540171
How inflammatory stimuli signal to the nucleus to restrict inflammation is poorly understood. Protein inhibitor of activated STAT1 (PIAS1), a transcriptional regulator that possesses small ubiquitin-related modifier (SUMO) E3 ligase...