Samuel M McCann
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Explore the profile of Samuel M McCann including associated specialties, affiliations and a list of published articles.
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36
Citations
907
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Recent Articles
1.
Rettori V, Fernandez-Solari J, Prestifilippo J, Mohn C, De Laurentiis A, Bornstein S, et al.
Neuroimmunomodulation
. 2007 Dec;
14(3-4):188-92.
PMID: 18073513
During marijuana and alcohol consumption as well as during inflammation the reproductive axis is inhibited, mainly through the inhibition of luteinizing hormone-releasing hormone release. In male rats, this inhibitory effect...
2.
Mastronardi C, Whelan F, Yildiz O, Hannestad J, Elashoff D, McCann S, et al.
Proc Natl Acad Sci U S A
. 2007 Apr;
104(17):7205-10.
PMID: 17409187
The systemic inflammatory response syndrome (SIRS) is a life-threatening medical condition characterized by a severe and generalized inflammatory state that can lead to multiple organ failure and shock. The CNS...
3.
Prestifilippo J, Fernandez-Solari J, Mohn C, De Laurentiis A, McCann S, Dees W, et al.
Toxicol Sci
. 2007 Feb;
97(1):75-80.
PMID: 17290048
Recently studies have demonstrated that low doses of (Mn(+2)) in the form of manganese chloride can stimulate specific puberty-related hormones and advance signs of pubertal development in immature female and...
4.
Sicard F, Ehrhart-Bornstein M, Corbeil D, Sperber S, Krug A, Ziegler C, et al.
Proc Natl Acad Sci U S A
. 2007 Feb;
104(6):2007-12.
PMID: 17264205
The adrenal gland comprises two endocrine tissues of distinct origin, the catecholamine-producing medulla and the steroid-producing cortex. The inner adrenocortical zone, which is in direct contact with the adrenomedullary chromaffin...
5.
Fernandez-Solari J, Prestifilippo J, Bornstein S, McCann S, Rettori V
Ann N Y Acad Sci
. 2006 Dec;
1088:238-50.
PMID: 17192570
It is known that Delta(9)-tetrahydrocannabinol (THC), the major active ingredient of marijuana, can suppress reproductive function. Also, we reported previously that the endocannabinoid, anandamide (AEA), inhibited gonadotropin-releasing hormone (LHRH) release...
6.
McCann S, De Laurentiis A, Rettori V
Ann N Y Acad Sci
. 2006 Dec;
1088:1-11.
PMID: 17192552
This review documents the remarkable progress over the last 50 years of our knowledge of the control of anterior pituitary hormone release and synthesis by a family of peptidic releasing...
7.
Scorticati C, Perazzo J, Rettori V, McCann S, De Laurentiis A
Neuroimmunomodulation
. 2006 Nov;
13(3):152-9.
PMID: 17119344
Objectives: Since very little is known about neuroendocrine changes that occur in portal-systemic hepatic encephalopathy, we studied plasma prolactin (PRL) levels and the involvement of hyperammonemia, nitric oxide (NO) and...
8.
Wong M, Whelan F, Deloukas P, Whittaker P, Delgado M, Cantor R, et al.
Proc Natl Acad Sci U S A
. 2006 Sep;
103(41):15124-9.
PMID: 17008408
Cyclic nucleotide phosphodiesterases (PDEs) constitute a family of enzymes that degrade cAMP and cGMP. Intracellular cyclic nucleotide levels increase in response to extracellular stimulation by hormones, neurotransmitters, or growth factors...
9.
Prestifilippo J, Fernandez-Solari J, de la Cal C, Iribarne M, Suburo A, Rettori V, et al.
Exp Biol Med (Maywood)
. 2006 Sep;
231(8):1421-9.
PMID: 16946411
It is known that marijuana use decreases saliva secretion. Therefore, we hypothesized that cannabinoid receptors (CBs) are located in salivary glands to mediate that effect. In these experiments, we used...
10.
de la Cal C, Lomniczi A, Mohn C, De Laurentiis A, Casal M, Chiarenza A, et al.
Neuroimmunomodulation
. 2006 May;
13(1):19-27.
PMID: 16691037
Objective: In the present work, we evaluated the effect of exposing the submandibular glands (SMG) to radiation, studying different functional parameters such as salivary secretion, nitric oxide (NO) production, reactive...