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Samuel Lobo

Explore the profile of Samuel Lobo including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Najafi S, Lobo S, Shell M, Shea J
J Phys Chem B . 2025 Feb; 129(7):1904-1915. PMID: 39907269
The interaction between amino acids (AAs) and hydration water is fundamental to protein folding and protein-protein interactions. Here, we proposed a hydrophobicity scale for AAs based on their computed free...
2.
Longhini A, DuBose A, Lobo S, Vijayan V, Bai Y, Rivera E, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(15):e2320456121. PMID: 38568974
Prion-like spread of disease-specific tau conformers is a hallmark of all tauopathies. A 19-residue probe peptide containing a P301L mutation and spanning the R2/R3 splice junction of tau folds and...
3.
Vigers M, Lobo S, Najafi S, DuBose A, Tsay K, Ganguly P, et al.
bioRxiv . 2023 Dec; PMID: 38077065
Significance Statement: This study presents a first step towards designing a tauopathy specific aggregation pathway by engineering a minimal tau prion building block, jR2R3, that can template and propagate distinct...
4.
Longhini A, DuBose A, Lobo S, Vijayan V, Bai Y, Rivera E, et al.
bioRxiv . 2023 Sep; PMID: 37693456
Prion-like spread of disease-specific tau conformers is a hallmark of all tauopathies. A 19-residue probe peptide containing a P301L mutation and spanning the R2/R3 splice junction of tau, folds and...