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Samuel L Jones

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Citations 610
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Recent Articles
11.
Sheats M, Pescosolido K, Hefner E, Sung E, Adler K, Jones S
Vet Immunol Immunopathol . 2014 May; 160(3-4):167-76. PMID: 24857637
Neutrophil infiltration is a prominent feature in a number of pathologic conditions affecting horses including recurrent airway obstruction, ischemia-reperfusion injury, and laminitis. Cell signaling components involved in neutrophil migration represent...
12.
Ott L, Sung E, Melvin A, Sheats M, Haugh J, Adler K, et al.
PLoS One . 2013 Jul; 8(6):e66512. PMID: 23840497
Myristoylated alanine-rich C-kinase substrate (MARCKS) is a ubiquitously expressed substrate of protein kinase C (PKC) that is involved in reorganization of the actin cytoskeleton. We hypothesized that MARCKS is involved...
13.
Li J, DAnnibale-Tolhurst M, Adler K, Fang S, Yin Q, Birkenheuer A, et al.
Am J Respir Cell Mol Biol . 2012 Dec; 48(3):314-21. PMID: 23221047
Myristoylated alanine-rich C kinase substrate (MARCKS) is a ubiquitously expressed protein kinase C substrate that has emerged as a potential therapeutic target for the amelioration of mucin secretion and inflammation...
14.
Royal L, Lascelles B, Lewbart G, Correa M, Jones S
J Zoo Wildl Med . 2012 Jul; 43(2):289-95. PMID: 22779232
This pilot study was designed to determine whether cyclooxygenase (COX)-1, COX-2, or both are expressed in normal turtle tissues and whether level of expression changes when tissue becomes inflamed. Five...
15.
Green T, Park J, Yin Q, Fang S, Crews A, Jones S, et al.
J Leukoc Biol . 2012 May; 92(3):633-9. PMID: 22623357
A role for MARCKS protein in directed migration of macrophages toward a chemoattractant was investigated. A peptide identical to the N-terminus of MARCKS (the MANS peptide), shown previously to inhibit...
16.
Ott L, McDowell Z, Turner P, Law J, Adler K, Yoder J, et al.
Anat Rec (Hoboken) . 2011 Aug; 294(9):1511-24. PMID: 21809467
Myristoylated alanine-rich C-kinase substrate (MARCKS) is an actin binding protein substrate of protein kinase C (PKC) and critical for mouse and Xenopus development. Herein two MARCKS paralogs, marcksa and marcksb,...
17.
Eckert R, Neuder L, Park J, Adler K, Jones S
Am J Respir Cell Mol Biol . 2009 Jul; 42(5):586-94. PMID: 19574534
Neutrophil migration into infected tissues is essential for host defense, but products of activated neutrophils can be quite damaging to host cells. Neutrophil influx into the lung and airways and...
18.
Cook V, Neuder L, Blikslager A, Jones S
Vet Immunol Immunopathol . 2009 Jan; 129(1-2):137-42. PMID: 19136156
The effect of lidocaine on in vitro migration and adhesion of equine neutrophils was evaluated. Neutrophils were isolated from equine whole blood using a Percoll-gradient centrifugation protocol. Purified neutrophils were...
19.
Eckert R, Sharief Y, Jones S
Vet Immunol Immunopathol . 2008 Dec; 129(3-4):181-91. PMID: 19095309
Equine laminar tissues do not contain resident neutrophils and have less superoxide dismutase (SOD) activity than other equine tissues, which makes them inherently more vulnerable to damage induced by reactive...
20.
Neuder L, Keener J, Eckert R, Trujillo J, Jones S
Vet Immunol Immunopathol . 2008 Dec; 129(3-4):192-9. PMID: 19070370
Endotoxemia occurs when bacterial lipopolysaccharide (LPS) in the blood induces a dysregulated inflammatory response, resulting in circulatory shock and multi-organ failure. Laminitis is a common complication in endotoxemic horses and...