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Samuel F Miller

Explore the profile of Samuel F Miller including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 642
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Recent Articles
1.
Behringer M, Ho W, Miller S, Worthan S, Cen Z, Stikeleather R, et al.
Curr Biol . 2024 Mar; 34(7):1403-1413.e5. PMID: 38460514
Microbes are evolutionarily robust organisms capable of rapid adaptation to complex stress, which enables them to colonize harsh environments. In nature, microbes are regularly challenged by starvation, which is a...
2.
Wei W, Ho W, Behringer M, Miller S, Bcharah G, Lynch M
Nat Commun . 2022 Aug; 13(1):4752. PMID: 35963846
Ecological and demographic factors can significantly shape the evolution of microbial populations both directly and indirectly, as when changes in the effective population size affect the efficiency of natural selection...
3.
Behringer M, Ho W, Meraz J, Miller S, Boyer G, Stone C, et al.
mBio . 2022 May; 13(3):e0346721. PMID: 35575545
Ecotypic diversification and its associated cooperative behaviors are frequently observed in natural microbial populations whose access to resources is often sporadic. However, the extent to which fluctuations in resource availability...
4.
Kucukyildirim S, Miller S, Lynch M
Ecol Evol . 2022 Jan; 11(24):17609-17614. PMID: 35003627
Analyses of spontaneous mutation have shown that total genome-wide mutation rates are quantitatively similar for most prokaryotic organisms. However, this view is mainly based on organisms that grow best around...
5.
Ho W, Behringer M, Miller S, Gonzales J, Nguyen A, Allahwerdy M, et al.
Genome Biol Evol . 2021 Dec; 13(12). PMID: 34864972
How microbes adapt to a novel environment is a central question in evolutionary biology. Although adaptive evolution must be fueled by beneficial mutations, whether higher mutation rates facilitate the rate...
6.
Long H, Miller S, Williams E, Lynch M
Mol Biol Evol . 2018 Jun; 35(10):2414-2421. PMID: 29939310
The mutation rate of an organism is influenced by the interaction of evolutionary forces such as natural selection and genetic drift. However, the mutation spectrum (i.e., the frequency distribution of...
7.
Behringer M, Choi B, Miller S, Doak T, Karty J, Guo W, et al.
Proc Natl Acad Sci U S A . 2018 May; 115(20):E4642-E4650. PMID: 29712844
How genetic variation is generated and maintained remains a central question in evolutionary biology. When presented with a complex environment, microbes can take advantage of genetic variation to exploit new...
8.
Senra M, Sung W, Ackerman M, Miller S, Lynch M, Soares C
Genome Biol Evol . 2018 Feb; 10(3):723-730. PMID: 29415256
Mutations contribute to genetic variation in all living systems. Thus, precise estimates of mutation rates and spectra across a diversity of organisms are required for a full comprehension of evolution....
9.
Long H, Sung W, Kucukyildirim S, Williams E, Miller S, Guo W, et al.
Nat Ecol Evol . 2018 Jan; 2(2):237-240. PMID: 29292397
One of the long-standing mysteries of evolutionary genomics is the source of the wide phylogenetic diversity in genome nucleotide composition (G + C versus A + T), which must be...
10.
Kucukyildirim S, Long H, Sung W, Miller S, Doak T, Lynch M
G3 (Bethesda) . 2016 May; 6(7):2157-63. PMID: 27194804
Mycobacterium smegmatis is a bacterium that is naturally devoid of known postreplicative DNA mismatch repair (MMR) homologs, mutS and mutL, providing an opportunity to investigate how the mutation rate and...