Samuel F M Hart
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Explore the profile of Samuel F M Hart including associated specialties, affiliations and a list of published articles.
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9
Citations
72
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Recent Articles
1.
Weinandt S, Child Z, Lartey D, Santos A, Maxfield H, Sevigny J, et al.
bioRxiv
. 2024 Dec;
PMID: 39677800
Bivalve transmissible neoplasia (BTN) is one of three known types of naturally transmissible cancer-cancers in which the whole cancer cells move from individual to individual, spreading through natural populations. BTN...
2.
Hart S, Garrett F, Kerr J, Metzger M
bioRxiv
. 2024 Sep;
PMID: 39345472
Transmissible cancers are unique instances in which cancer cells escape their original host and spread through a population as a clonal lineage, documented in Tasmanian Devils, dogs, and ten bivalve...
3.
Hart S, Yonemitsu M, Giersch R, Garrett F, Beal B, Arriagada G, et al.
Nat Cancer
. 2023 Oct;
4(11):1561-1574.
PMID: 37783804
Transmissible cancers are infectious parasitic clones that metastasize to new hosts, living past the death of the founder animal in which the cancer initiated. We investigated the evolutionary history of...
4.
Michnowska A, Hart S, Smolarz K, Hallmann A, Metzger M
Mol Ecol
. 2022 Apr;
31(11):3128-3136.
PMID: 35403750
Disseminated neoplasia (DN) is one of the most challenging and unrecognised diseases occurring in aquatic fauna. It has been diagnosed in four bivalve species from the Gulf of Gdańsk (Southern...
5.
Giersch R, Hart S, Reddy S, Yonemitsu M, Orellana Rosales M, Korn M, et al.
Pathogens
. 2022 Mar;
11(3).
PMID: 35335607
Many pathogens can cause cancer, but cancer itself does not normally act as an infectious agent. However, transmissible cancers have been found in a few cases in nature: in Tasmanian...
6.
Green R, Sonal , Wang L, Hart S, Lu W, Skelding D, et al.
PLoS Biol
. 2020 Aug;
18(8):e3000757.
PMID: 32833957
In eukaryotes, conserved mechanisms ensure that cell growth is coordinated with nutrient availability. Overactive growth during nutrient limitation ("nutrient-growth dysregulation") can lead to rapid cell death. Here, we demonstrate that...
7.
Hart S, Skelding D, Waite A, Burton J, Shou W
Quant Biol
. 2019 Oct;
7(1):69-81.
PMID: 31598381
Background: Microbes live in dynamic environments where nutrient concentrations fluctuate. Quantifying fitness in terms of birth rate and death rate in a wide range of environments is critical for understanding...
8.
Skelding D, Hart S, Vidyasagar T, Pozhitkov A, Shou W
Quant Biol
. 2019 Oct;
6(2):129-141.
PMID: 31598380
Background: Multiplexed milliliter-scale chemostats are useful for measuring cell physiology under various degrees of nutrient limitation and for carrying out evolution experiments. In each chemostat, fresh medium containing a growth...
9.
Hart S, Mi H, Green R, Xie L, Pineda J, Momeni B, et al.
PLoS Biol
. 2019 Feb;
17(2):e3000135.
PMID: 30794534
Quantitative modeling is useful for predicting behaviors of a system and for rationally constructing or modifying the system. The predictive power of a model relies on accurate quantification of model...