Samu Kainulainen
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Explore the profile of Samu Kainulainen including associated specialties, affiliations and a list of published articles.
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41
Citations
205
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Recent Articles
1.
Sigurdardottir S, Pitkanen H, Korkalainen H, Kainulainen S, Serwatko M, Olafsdottir K, et al.
J Sleep Res
. 2025 Feb;
:e70012.
PMID: 39949045
Polysomnography is the only internationally recognized method to diagnose paediatric obstructive sleep apnea, thus, simpler and more cost-effective diagnostic tools are urgently needed. This study aimed to validate the manual...
2.
Howarth T, Hietakoste S, Ebrahimian S, Rissanen M, Kainulainen S, Karhu T
J Sleep Res
. 2025 Feb;
:e14459.
PMID: 39905694
Sleep stages exhibit differing patterns of cardiac, respiratory and nervous system activation. Rapid eye movement (REM) sleep is associated with deeper oxygen desaturation events in obstructive sleep apnea. However, no...
3.
Hietakoste S, Karhu T, Lombardi C, Armanac-Julian P, Bailon R, Duce B, et al.
Sleep
. 2024 Dec;
PMID: 39670869
In obstructive sleep apnea (OSA), heart rate variability (HRV) decreases and performance in psychomotor vigilance task (PVT) worsens with more severe hypoxic load. Nevertheless, the association between HRV and PVT...
4.
Staykov E, Mann D, Kainulainen S, Leppanen T, Toyras J, Azarbarzin A, et al.
medRxiv
. 2024 Nov;
PMID: 39606366
Rationale: Excessive daytime sleepiness, an important symptom of obstructive sleep apnea (OSA), is commonly quantified using the Epworth Sleepiness Scale score (ESS). Baseline OSA severity measures (ventilatory burden, flow limitation,...
5.
Pitkanen M, Pitkanen H, Nath R, Nikkonen S, Kainulainen S, Korkalainen H, et al.
J Sleep Res
. 2024 Nov;
:e14391.
PMID: 39496283
Obstructive sleep apnea diagnosis is based on the manual scoring of respiratory events. The agreement in the manual scoring of the respiratory events lacks an in-depth investigation as most of...
6.
Sillanmaki S, Ebrahimian S, Hietakoste S, Hernando D, Bailon R, Leppanen T, et al.
ERJ Open Res
. 2024 Oct;
10(5).
PMID: 39469266
Aims: Obstructive sleep apnoea (OSA) imposes significant stress on the cardiovascular system and the heart. While long-term cardiac effects are understood, the immediate impact of hypoxaemia on the heart's electrophysiology...
7.
Rusanen M, Jouan G, Huttunen R, Nikkonen S, Sigurdardottir S, Toyras J, et al.
J Sleep Res
. 2024 Oct;
:e14362.
PMID: 39443165
State-of-the-art automatic sleep staging methods have demonstrated comparable reliability and superior time efficiency to manual sleep staging. However, fully automatic black-box solutions are difficult to adapt into clinical workflow due...
8.
Pitkanen M, Huovinen J, Rissanen M, Pitkanen H, Kainulainen S, Penzel T, et al.
J Clin Sleep Med
. 2024 Oct;
21(2):337-344.
PMID: 39364956
Study Objectives: Arousal burden (AB) is defined as the cumulative duration of arousals during sleep divided by the total sleep time. However, in-depth analysis of AB related to sleep characteristics...
9.
Chen X, Leppanen T, Kainulainen S, Howarth T, Oksenberg A, Toyras J, et al.
J Clin Sleep Med
. 2024 May;
20(10):1595-1606.
PMID: 38722264
Study Objectives: Excessive daytime sleepiness (EDS) in patients with obstructive sleep apnea is poorly explained by standard clinical sleep architecture metrics. We hypothesized that reduced sleep stage continuity mediates this...
10.
Howarth T, Sillanmaki S, Karhu T, Rissanen M, Islind A, Hrubos-Strom H, et al.
Sleep Med
. 2024 Apr;
118:101-112.
PMID: 38657349
Background: There are strong associations between oxygen desaturations and cardiovascular outcomes. Additionally, oxygen resaturation rates are linked to excessive daytime sleepiness independent of oxygen desaturation severity. No studies have yet...