Samreen Gul Khan
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Explore the profile of Samreen Gul Khan including associated specialties, affiliations and a list of published articles.
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30
Citations
80
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Recent Articles
11.
Akhter N, Batool S, Khan S, Rasool N, Anjum F, Rasul A, et al.
Pharmaceuticals (Basel)
. 2023 Jun;
16(2).
PMID: 37259360
Triazole-based acetamides serve as important scaffolds for various pharmacologically active drugs. In the present work, structural hybrids of 1,2,4-triazole and acetamides were furnished by chemically modifying 2-(4-isobutylphenyl) propanoic acid ()....
12.
Noor R, Zahoor A, Mansha A, Khan S, Haq A, Ahmad S, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047665
Ring expansion reactions fascinate synthetic chemists owing to their importance in synthesizing biologically active compounds and their efficacy in medicinal chemistry. The present review summarizes a number of synthetic methodologies,...
13.
Akhtar R, Zahoor A, Mansha A, Kamal S, Khan S, Raza Z, et al.
PLoS One
. 2023 Mar;
18(3):e0281044.
PMID: 37000820
In this study, we have investigated ciprofloxacin-based acetanilides for their in-vitro inhibitory study against gram +ve, -ve bacteria and serine protease activity. The compounds 4e and 4g showed excellent antibacterial...
14.
Mahmood S, Khan S, Rasul A, Christensen J, Abourehab M
Molecules
. 2022 Nov;
27(22).
PMID: 36432091
The development of an economical method for the synthesis of biologically active compounds was the major goal of this research. In the present study, we have reported the ultrasound-radiation-assisted synthesis...
15.
Shahzadi I, Parveen B, Ahmad S, Khan S, Zahoor A, Rasul A, et al.
Pak J Pharm Sci
. 2022 Jul;
35(3(Special)):885-889.
PMID: 35791583
Hydrazones of theophylline-7-acetic acid 5a-g have been synthesized using ultrasonic irradiation as well as conventional heating system and analyzed for their anticancer characteristics against human lung cancer cell line (A549)....
16.
Iqbal N, Zahoor A, Rasool N, Khan S, Akhtar R, Ahmad R
Curr Org Synth
. 2021 Dec;
PMID: 34951368
Background: Tubulysins, linear tetrapeptides show extraordinary cytotoxicity against various cancer cells, with IC50 values in nano or picomolar range. Due to their extremely vigorous anti-proliferative and antiangiogenic characteristics, tubulysins exhibit...
17.
Ahmad S, Taj S, Aslam S, Khan S, Farooq T, Ashfaq U, et al.
Pak J Pharm Sci
. 2021 Nov;
34(5(Supplementary)):1951-1955.
PMID: 34836865
Diabetes mellitus (DM) is a metabolic disorder characterized by frequent urination, hunger and high blood sugar level. α-glucosidase inhibitors are considered as a frontline treatment for the DM. This research...
18.
Hafeez F, Mansha A, Zahoor A, Ali K, Khan S, Naqvi S
Pak J Pharm Sci
. 2021 Nov;
34(5(Supplementary)):1885-1890.
PMID: 34836855
The facile and efficient protocol for the synthesis of N-phenyl piperazine based di-thio-carbamates has been reported under neat conditions. A library of novel piperazine based di-thio-carbamates (3a-h) in excellent yields...
19.
Akhtar R, Zahoor A, Rasul A, Khan S, Ali K
Pak J Pharm Sci
. 2021 Oct;
34(3(Supplementary)):1143-1148.
PMID: 34602444
Fluoroquinolones are targets of interest due to their broad spectrum antibacterial activity. Structure-activity relationship (SAR) of fluoroquinolones clearly indicates that substitution at C-7 position enhances the lipophilicity of these scaffolds...
20.
Ur-Rehman A, Khan S, Naqvi S, Ahmad M, Akhtar N, Bokhari T, et al.
Pak J Pharm Sci
. 2021 Jul;
34(1(Special)):441-446.
PMID: 34275792
A series of new derivatives of 4-(2-chloroethyl)morpholine hydrochloride (5) were efficiently synthesized. Briefly, different aromatic organic acids (1a-f) were refluxed to acquire respective esters (2a-f) using conc. HSO as catalyst....