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Sampath K T Kapanaiah

Explore the profile of Sampath K T Kapanaiah including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 57
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Recent Articles
1.
Kapanaiah S, Grimm C, Katzel D
Schizophrenia (Heidelb) . 2024 Oct; 10(1):90. PMID: 39379378
Hyperactivity of the human anterior hippocampus has been reported to spread from its CA1 subfield to the subiculum around the onset of first-episode psychosis and could be a cellular target...
2.
Kapanaiah S, Rosenbrock H, Hengerer B, Katzel D
Front Pharmacol . 2024 Jul; 15:1412725. PMID: 39045050
Background: Neuropsychopharmacological compounds may exert complex brain-wide effects due to an anatomically and genetically broad expression of their molecular targets and indirect effects interconnected brain circuits. Electrophysiological measurements in multiple...
3.
Jendryka M, Lewin U, van der Veen B, Kapanaiah S, Prex V, Strahnen D, et al.
Transl Psychiatry . 2023 Jul; 13(1):243. PMID: 37407615
The anterior cingulate cortex (ACC) has been implicated in attention deficit hyperactivity disorder (ADHD). More specifically, an appropriate balance of excitatory and inhibitory activity in the ACC may be critical...
4.
Kapanaiah S, Katzel D
HardwareX . 2023 May; 14:e00429. PMID: 37250189
In vivo electro- and optophysiology experiments in rodents reveal the neural mechanisms underlying behavior and brain disorders but mostly involve a cable connection between an implant in the animal and...
5.
Buhner L, Kapanaiah S, Katzel D
Front Behav Neurosci . 2022 Oct; 16:1002223. PMID: 36225391
Schizophrenia is a severe psychiatric disorder whose neurodevelopmental pathogenesis includes a prodromal phase before its diagnostically decisive-namely psychotic-symptoms are present. This prodrome is characterized by cognitive and affective deficits, and...
6.
Roy D, Puvvada M, Kapanaiah S, Patel A
Neurochem Res . 2022 Mar; 47(6):1765-1777. PMID: 35347633
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with selective degeneration of motor neurons in the central nervous system. The pathophysiology of ALS is not well understood. We have...
7.
Kilonzo K, Strahnen D, Prex V, Gems J, van der Veen B, Kapanaiah S, et al.
Transl Psychiatry . 2022 Mar; 12(1):102. PMID: 35288531
Schizophrenia is associated with a broad range of severe and currently pharmacoresistant cognitive deficits. Prior evidence suggests that hypofunction of AMPA-type glutamate receptors (AMPARs) containing the subunit GLUA1, encoded by...
8.
Kapanaiah S, van der Veen B, Strahnen D, Akam T, Katzel D
Sci Rep . 2021 Nov; 11(1):22279. PMID: 34782697
Operant boxes enable the application of complex behavioural paradigms to support circuit neuroscience and drug discovery research. However, commercial operant box systems are expensive and often not optimised for combining...
9.
van der Veen B, Kapanaiah S, Kilonzo K, Steele-Perkins P, Jendryka M, Schulz S, et al.
Commun Biol . 2021 Jun; 4(1):662. PMID: 34079054
Pathological impulsivity is a debilitating symptom of multiple psychiatric diseases with few effective treatment options. To identify druggable receptors with anti-impulsive action we developed a systematic target discovery approach combining...
10.
Kilonzo K, van der Veen B, Teutsch J, Schulz S, Kapanaiah S, Liss B, et al.
Sci Rep . 2021 Apr; 11(1):8788. PMID: 33888809
A hypofunction of N-methyl-D-aspartate glutamate receptors (NMDARs) has been implicated in the pathogenesis of schizophrenia by clinical and rodent studies. However, to what extent NMDAR-hypofunction in distinct cell-types across the...