Sambit K Mishra
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Explore the profile of Sambit K Mishra including associated specialties, affiliations and a list of published articles.
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10
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73
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Recent Articles
1.
Sannigrahi M, Raghav L, Rich D, Schrank T, Califano J, Lukens J, et al.
J Natl Cancer Inst
. 2025 Mar;
PMID: 40069922
Background: Limited understanding of the biology predisposing certain human papillomavirus-related (HPV+) oropharyngeal squamous cell carcinomas (OPSCCs) to relapse impedes therapeutic personalization. We aimed to identify molecular traits that distinguish recurrence-prone...
2.
Robinson E, Rodriguez I, Argueta V, Xie Y, Lou H, Milano R, et al.
Tumour Virus Res
. 2024 Dec;
19():200299.
PMID: 39672307
To better understand cervical cancer progression, we analyzed RNA from 262 biopsies from women referred for colposcopy. We determined the HPV type and analyzed the expression of 51 genes. HPV31...
3.
Sannigrahi M, Raghav L, Rich D, Schrank T, Califano J, Lukens J, et al.
bioRxiv
. 2024 Nov;
PMID: 39574723
Background: Limited understanding of the biology predisposing certain human papillomavirus-related (HPV+) oropharyngeal squamous cell carcinomas (OPSCCs) to relapse impedes therapeutic personalization. We aimed to identify molecular traits that distinguish recurrence-prone...
4.
Mishra S, Nelson C, Zhu B, Pinheiro M, Lee H, Dean M, et al.
Virus Evol
. 2024 Mar;
10(1):veae013.
PMID: 38455683
High-coverage sequencing allows the study of variants occurring at low frequencies within samples, but is susceptible to false-positives caused by sequencing error. Ion Torrent has a very low single nucleotide...
5.
Liu S, Xiao Z, Mishra S, Mitchell J, Smith J, Quarles L, et al.
J Chem Inf Model
. 2022 Jul;
62(15):3627-3637.
PMID: 35868851
Fibroblast growth factor 23 (FGF23) is a therapeutic target for treating hereditary and acquired hypophosphatemic disorders, such as X-linked hypophosphatemic (XLH) rickets and tumor-induced osteomalacia (TIO), respectively. FGF23-induced hypophosphatemia is...
6.
Rodrigues T, Mishra S, Sridharan K, Barnes E, Alyokhin A, Tuttle R, et al.
Front Plant Sci
. 2021 Dec;
12:728652.
PMID: 34887882
Colorado potato beetle (CPB, ) is a major pest of potato and other solanaceous vegetables in the Northern Hemisphere. The insect feeds on leaves and can completely defoliate crops. Because...
7.
Mishra S, Cooper C, Parks J, Mitchell J
J Phys Chem B
. 2021 Jun;
125(23):6058-6067.
PMID: 34077660
Protein-protein interactions play a key role in mediating numerous biological functions, with more than half the proteins in living organisms existing as either homo- or hetero-oligomeric assemblies. Protein subunits that...
8.
Mishra S, Muthye V, Kandoi G
Int J Mol Sci
. 2020 Aug;
21(16).
PMID: 32784445
Multiple mRNA isoforms of the same gene are produced via alternative splicing, a biological mechanism that regulates protein diversity while maintaining genome size. Alternatively spliced mRNA isoforms of the same...
9.
Jia M, Mishra S, Tufts S, Jernigan R, Peters R
Metab Eng
. 2019 Jun;
55:44-58.
PMID: 31220664
Terpene synthases are capable of mediating complex reactions, but fundamentally simply catalyze lysis of allylic diphosphate esters with subsequent deprotonation. Even with the initially generated tertiary carbocation this offers a...
10.
Mishra S, Kandoi G, Jernigan R
Proteins
. 2019 May;
87(10):850-868.
PMID: 31141211
Binding sites in proteins can be either specifically functional binding sites (active sites) that bind specific substrates with high affinity or regulatory binding sites (allosteric sites), that modulate the activity...