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Samantha J Falk

Explore the profile of Samantha J Falk including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 306
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Recent Articles
1.
Iwata-Otsubo A, Dawicki-McKenna J, Akera T, Falk S, Chmatal L, Yang K, et al.
Curr Biol . 2017 Aug; 27(15):2365-2373.e8. PMID: 28756949
Female meiosis provides an opportunity for selfish genetic elements to violate Mendel's law of segregation by increasing the chance of segregating to the egg [1]. Centromeres and other repetitive sequences...
2.
Falk S, Lee J, Sekulic N, Sennett M, Lee T, Black B
Nat Struct Mol Biol . 2016 Feb; 23(3):204-208. PMID: 26878239
The histone H3 variant CENP-A is incorporated into nucleosomes that mark centromere location. We have recently reported that CENP-A nucleosomes, compared with their H3 counterparts, confer an altered nucleosome shape....
3.
Wei S, Falk S, Black B, Lee T
Nucleic Acids Res . 2015 May; 43(17):e111. PMID: 26013809
Structural dynamics of nucleic acid and protein is an important physical basis of their functions. These motions are often very difficult to synchronize and too fast to be clearly resolved...
4.
Falk S, Guo L, Sekulic N, Smoak E, Mani T, Logsdon G, et al.
Science . 2015 May; 348(6235):699-703. PMID: 25954010
Inheritance of each chromosome depends upon its centromere. A histone H3 variant, centromere protein A (CENP-A), is essential for epigenetically marking centromere location. We find that CENP-A is quantitatively retained...
5.
Falk S, Black B
Biochim Biophys Acta . 2014 Jan; 1819(3-4):313-21. PMID: 24459733
The centromere is the locus that directs chromosomal inheritance at cell division. While centromeres in diverse eukaryotes are commonly found at sites of repetitive DNA, their location is epigenetically specified....
6.
Falk S, Black B
Biochim Biophys Acta . 2011 Dec; 1819(3-4):313-21. PMID: 22154124
The centromere is the locus that directs chromosomal inheritance at cell division. While centromeres in diverse eukaryotes are commonly found at sites of repetitive DNA, their location is epigenetically specified....