Samantha C Waterworth
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Explore the profile of Samantha C Waterworth including associated specialties, affiliations and a list of published articles.
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12
Citations
94
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Recent Articles
1.
Waterworth S, Shenoy S, Sharma N, Wolcott C, Donohue D, OKeefe B, et al.
Protein Sci
. 2025 Feb;
34(3):e70055.
PMID: 39989223
Differential scanning fluorimetry (DSF) can be an effective high-throughput screening assay in drug discovery for detecting protein-compound interactions that stabilize or destabilize macromolecules. Due to the magnitude and quality of...
2.
Waterworth S, Solomons G, Kalinski J, Madonsela L, Parker-Nance S, Dorrington R
mSphere
. 2024 Nov;
9(12):e0084524.
PMID: 39570026
Bacterial symbionts are critical members of many marine sponge holobionts. Some sponge-associated bacterial lineages, such as Poribacteria, sponge-associated unclassified lineage (SAUL), and Tethybacterales, appear to have broad-host ranges and associate...
3.
Uppal S, Waterworth S, Nick A, Vogel H, Florez L, Kaltenpoth M, et al.
ISME J
. 2024 Oct;
18(1).
PMID: 39441990
Microbial symbionts associate with multicellular organisms on a continuum from facultative associations to mutual codependency. In the oldest intracellular symbioses there is exclusive vertical symbiont transmission, and co-diversification of symbiotic...
4.
Uppal S, Waterworth S, Nick A, Vogel H, Florez L, Kaltenpoth M, et al.
bioRxiv
. 2024 Jul;
PMID: 39026795
Microbial symbionts associate with multicellular organisms on a continuum from facultative associations to mutual codependency. In some of the oldest intracellular symbioses there is exclusive vertical symbiont transmission, and co-diversification...
5.
Neuhaus G, Aron A, Isemonger E, Petras D, Waterworth S, Madonsela L, et al.
PLoS One
. 2024 May;
19(5):e0303273.
PMID: 38781236
Lithified layers of complex microbial mats known as microbialites are ubiquitous in the fossil record, and modern forms are increasingly identified globally. A key challenge to developing an understanding of...
6.
Kalinski J, Polyzois A, Waterworth S, Siwe Noundou X, Dorrington R
Molecules
. 2022 Dec;
27(24).
PMID: 36557854
Pyrroloiminoquinones are a group of cytotoxic alkaloids most commonly isolated from marine sponges. Structurally, they are based on a tricyclic pyrrolo[4,3,2-de]quinoline core and encompass marine natural products such as makaluvamines,...
7.
Waterworth S, Parker-Nance S, Kwan J, Dorrington R
mBio
. 2021 Sep;
12(5):e0157721.
PMID: 34519538
The fossil record indicates that the earliest evidence of extant marine sponges (phylum Porifera) existed during the Cambrian explosion and that their symbiosis with microbes may have begun in their...
8.
Kalinski J, Krause R, Parker-Nance S, Waterworth S, Dorrington R
Mar Drugs
. 2021 Feb;
19(2).
PMID: 33525412
Sponges of the Latrunculiidae family produce bioactive pyrroloiminoquinone alkaloids including makaluvamines, discorhabdins, and tsitsikammamines. The aim of this study was to use LC-ESI-MS/MS-driven molecular networking to characterize the pyrroloiminoquinone secondary...
9.
Waterworth S, Isemonger E, Rees E, Dorrington R, Kwan J
Environ Microbiol Rep
. 2020 Dec;
13(2):126-137.
PMID: 33369160
Stromatolites are complex microbial mats that form lithified layers. Fossilized stromatolites are the oldest evidence of cellular life on Earth, dating back over 3.4 billion years. Modern stromatolites are relatively...
10.
Waterworth S, Florez L, Rees E, Hertweck C, Kaltenpoth M, Kwan J
mBio
. 2020 Feb;
11(1).
PMID: 32098813
Symbiotic mutualisms of bacteria and animals are ubiquitous in nature, running a continuum from facultative to obligate from the perspectives of both partners. The loss of functions required for living...