Samanta C Funes
Overview
Explore the profile of Samanta C Funes including associated specialties, affiliations and a list of published articles.
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13
Citations
571
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0
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Recent Articles
1.
Mora V, Quero F, Troncoso-Bravo T, Orellana C, Pereira P, Mackern-Oberti J, et al.
Autoimmunity
. 2024 Jul;
57(1):2380465.
PMID: 39034498
Systemic Lupus Erythematosus (SLE) is an autoimmune disorder that causes a breakdown of immune tolerance. Current treatments mainly involve general immunosuppression, increasing the risk of infections. On the other hand,...
2.
Arias J, Funes S, Blas R, Callegari E, Elicabe R, Paez M, et al.
Front Immunol
. 2023 Jan;
13:1077914.
PMID: 36700196
Introduction: Spondyloarthritis (SpA) is a common autoinflammatory disease. S100A8/ S100A9 alarmin is strongly expressed in the synovial sublining layers of psoriatic arthritis. S100A8/ S100A9 is the most abundant protein in...
3.
Funes S, Rios M, Fernandez-Fierro A, Rivera-Perez D, Soto J, Valbuena J, et al.
Front Immunol
. 2022 Sep;
13:966917.
PMID: 36159799
Maternal thyroid hormones (THs) are essential for the appropriate development of the fetus and especially for the brain. Recently, some studies have shown that THs deficiency can also alter the...
4.
Funes S, Rios M, Fernandez-Fierro A, Di Genaro M, Kalergis A
Front Immunol
. 2022 Apr;
13:868343.
PMID: 35464438
A dysregulated immune response toward self-antigens characterizes autoimmune and autoinflammatory (AIF) disorders. Autoantibodies or autoreactive T cells contribute to autoimmune diseases, while autoinflammation results from a hyper-functional innate immune system....
5.
Funes S, Fernandez-Fierro A, Rebolledo-Zelada D, Mackern-Oberti J, Kalergis A
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769338
Epigenetic mechanisms, such as DNA methylation, histone modifications, and non-coding RNAs are known regulators of gene expression and genomic stability in cell growth, development, and differentiation. Because epigenetic mechanisms can...
6.
Fernandez-Fierro A, Funes S, Rios M, Covian C, Gonzalez J, Kalergis A
Int J Mol Sci
. 2021 Jan;
22(1).
PMID: 33396647
The heme oxygenase (HO) system involves three isoforms of this enzyme, HO-1, HO-2, and HO-3. The three of them display the same catalytic activity, oxidating the heme group to produce...
7.
Funes S, Rios M, Fernandez-Fierro A, Covian C, Bueno S, Riedel C, et al.
Front Immunol
. 2020 Aug;
11:1467.
PMID: 32849503
Heme oxygenase (HO) is the primary antioxidant enzyme involved in heme group degradation. A variety of stimuli triggers the expression of the inducible HO-1 isoform, which is modulated by its...
8.
Funes S, Rios M, Gomez-Santander F, Fernandez-Fierro A, Altamirano-Lagos M, Rivera-Perez D, et al.
Immunology
. 2019 Sep;
158(4):322-339.
PMID: 31509246
Current treatments for systemic autoimmune diseases partially improve the health of patients displaying low pharmacological efficacy and systemic immunosuppression. Here, the therapeutic potential of transferring tolerogenic dendritic cells (tolDCs) generated...
9.
Funes S, Manrique de Lara A, Altamirano-Lagos M, Mackern-Oberti J, Escobar-Vera J, Kalergis A
Autoimmun Rev
. 2019 Feb;
18(4):359-368.
PMID: 30738957
The immune system is responsible for defending the host from a large variety of potential pathogens, while simultaneously avoiding immune reactivity towards self-components. Self-tolerance has to be tightly maintained throughout...
10.
Funes S, Mansilla M, Canedo-Marroquin G, Lay M, Riedel C, Kalergis A
Curr Pharm Des
. 2018 Aug;
24(30):3495-3505.
PMID: 30156146
Reducing infant mortality due to infectious diseases is one of the most important public health goals worldwide. Several approaches have been implemented to reach this goal and vaccination has been...