Sam Horng
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Explore the profile of Sam Horng including associated specialties, affiliations and a list of published articles.
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20
Citations
887
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Recent Articles
1.
Amatruda M, Turati J, Weiss J, Villavicencio J, Chen Z, Britton G, et al.
Brain Behav
. 2025 Feb;
15(2):e70239.
PMID: 39910805
Introduction: The transgenic murine Cre/loxP system is deployed to investigate the role of central nervous system (CNS) cell-specific gene alterations in both healthy conditions and models of neurologic disease. The...
2.
Mora P, Laisne M, Bourguignon C, Rouault P, Jaspard-Vinassa B, Maitre M, et al.
J Neuroinflammation
. 2024 Oct;
21(1):258.
PMID: 39390606
Under neuroinflammatory conditions, astrocytes acquire a reactive phenotype that drives acute inflammatory injury as well as chronic neurodegeneration. We hypothesized that astrocytic Delta-like 4 (DLL4) may interact with its receptor...
3.
Sand I, Gnjatic S, Krammer F, Tuballes K, Carreno J, Satyanarayan S, et al.
Mult Scler Relat Disord
. 2023 Jan;
70:104486.
PMID: 36628884
Background: People living with multiple sclerosis (MS) and other disorders treated with immunomodulatory therapies remain concerned about suboptimal responses to coronavirus disease 2019 (COVID-19) vaccines. Important questions persist regarding immunological...
4.
Sand I, Gnjatic S, Krammer F, Tuballes K, Carreno J, Satyanarayan S, et al.
medRxiv
. 2022 Jun;
PMID: 35734083
Importance: People living with multiple sclerosis (MS) and other disorders treated with immunomodulatory therapies remain concerned about suboptimal responses to coronavirus disease 2019 (COVID-19) vaccines. Important questions persist regarding immunological...
5.
Satyanarayan S, Safi N, Sorets T, Filomena S, Zhang Y, Klineova S, et al.
Mult Scler Relat Disord
. 2022 May;
62:103737.
PMID: 35533419
Background: Prior studies suggest reduced humoral response to COVID-19 vaccination in immunosuppressed populations. Disease modifying therapies (DMTs) for multiple sclerosis (MS) have variable immunomodulatory effects, and limited data are available...
6.
Amatruda M, Chapouly C, Woo V, Safavi F, Zhang J, Dai D, et al.
Brain Commun
. 2022 Mar;
4(2):fcac044.
PMID: 35265839
Contact-mediated interactions between the astrocytic endfeet and infiltrating immune cells within the perivascular space are underexplored, yet represent potential regulatory check-points against CNS autoimmune disease and disability. Reactive astrocytes upregulate...
7.
Sumowski J, Horng S, Brandstadter R, Krieger S, Leavitt V, Sand I, et al.
Ann Clin Transl Neurol
. 2021 May;
8(6):1172-1182.
PMID: 33951348
Objective: Sleep-dependent memory processing occurs in animals including humans, and disturbed sleep negatively affects memory. Sleep disturbance and memory dysfunction are common in multiple sclerosis (MS), but little is known...
8.
Mora P, Hollier P, Guimbal S, Abelanet A, Diop A, Cornuault L, et al.
PLoS Biol
. 2020 Nov;
18(11):e3000946.
PMID: 33253145
Inflammation of the central nervous system (CNS) induces endothelial blood-brain barrier (BBB) opening as well as the formation of a tight junction barrier between reactive astrocytes at the Glia Limitans....
9.
Jordan S, Tung N, Casanova-Acebes M, Chang C, Cantoni C, Zhang D, et al.
Cell
. 2019 Aug;
178(5):1102-1114.e17.
PMID: 31442403
Caloric restriction is known to improve inflammatory and autoimmune diseases. However, the mechanisms by which reduced caloric intake modulates inflammation are poorly understood. Here we show that short-term fasting reduced...
10.
Harel A, Horng S, Gustafson T, Ramineni A, Straus Farber R, Fabian M
J Neurovirol
. 2018 Jul;
24(5):652-655.
PMID: 29987583
Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, often fatal viral infection of the brain without a known treatment. Recently, case reports have demonstrated survival from PML with therapies that...