Sally K Martin
Overview
Explore the profile of Sally K Martin including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
399
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0
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Recent Articles
1.
Tangseefa P, Martin S, Arthur A, Panagopoulos V, Page A, Wittert G, et al.
JBMR Plus
. 2021 May;
5(5):e10486.
PMID: 33977204
The mammalian target of rapamycin complex 1 (mTORC1) complex is the major nutrient sensor in mammalian cells that responds to amino acids, energy levels, growth factors, and hormones, such as...
2.
Tangseefa P, Martin S, Chin P, Breen J, Mah C, Baldock P, et al.
Bone Res
. 2021 Feb;
9(1):10.
PMID: 33551450
Overnutrition causes hyperactivation of mTORC1-dependent negative feedback loops leading to the downregulation of insulin signaling and development of insulin resistance. In osteoblasts (OBs), insulin signaling plays a crucial role in...
3.
Martin S, Fitter S, El Khawanky N, Grose R, Walkley C, Purton L, et al.
Sci Rep
. 2018 Sep;
8(1):14501.
PMID: 30266921
Skeletal osteoblasts are important regulators of B-lymphopoiesis, serving as a rich source of factors such as CXCL12 and IL-7 which are crucial for B-cell development. Recent studies from our laboratory...
4.
Vandyke K, Zeissig M, Hewett D, Martin S, Mrozik K, Cheong C, et al.
Cancer Res
. 2017 Sep;
77(20):5452-5463.
PMID: 28855206
Disease progression and relapse in multiple myeloma is dependent on the ability of the multiple myeloma plasma cells (PC) to reenter the circulation and disseminate throughout the bone marrow. Increased...
5.
Tangseefa P, Martin S, Fitter S, Baldock P, Proud C, Zannettino A
J Cell Physiol
. 2017 Aug;
233(5):3769-3783.
PMID: 28834550
The skeleton has recently emerged as a critical insulin target tissue that regulates whole body glucose metabolism and male reproductive function. While our understanding of these new regulatory axes remains...
6.
Fitter S, Matthews M, Martin S, Xie J, Ooi S, Walkley C, et al.
Mol Cell Biol
. 2017 Jan;
37(7).
PMID: 28069737
The mammalian target of rapamycin complex 1 (mTORC1) is activated by extracellular factors that control bone accrual. However, the direct role of this complex in osteoblast biology remains to be...
7.
Cheong C, Chow A, Fitter S, Hewett D, Martin S, Williams S, et al.
Exp Cell Res
. 2015 Feb;
332(1):24-38.
PMID: 25637218
Background: Increased expression of the tetraspanin TSPAN7 has been observed in a number of cancers; however, it is unclear how TSPAN7 plays a role in cancer progression. Methods: We investigated...
8.
Martin S, Gan Z, Fitter S, To L, Zannettino A
Leuk Res
. 2015 Jan;
39(3):380-7.
PMID: 25624048
The plasma cell malignancy multiple myeloma (MM) is unique amongst haematological malignancies in its capacity to cause osteoclast-mediated skeletal destruction. The PI3K/Akt pathway mediates proliferation, survival and drug resistance in...
9.
Martin S, Fitter S, Dutta A, Matthews M, Walkley C, Hall M, et al.
Stem Cells
. 2014 Dec;
33(4):1359-65.
PMID: 25537496
Adipocytes (AdCs) and osteoblasts (OBs) are derived from mesenchymal stem cells (MSCs) and differentiation toward either lineage is both mutually exclusive and transcriptionally controlled. Recent studies implicate the mammalian target...
10.
Gan Z, Fitter S, Vandyke K, To L, Zannettino A, Martin S
Eur J Haematol
. 2014 Sep;
94(4):343-54.
PMID: 25179233
The plasma cell malignancy multiple myeloma (MM) is unique among haematological malignancies in its capacity to cause osteoclast-mediated skeletal destruction. The PI3K/Akt/mTOR pathway mediates proliferation, survival and drug resistance in...