Sajad Moshkelgosha
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Explore the profile of Sajad Moshkelgosha including associated specialties, affiliations and a list of published articles.
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30
Citations
299
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Recent Articles
1.
Levy L, Moshkelgosha S, Huszti E, Wang S, Hunter S, Zhang C, et al.
J Heart Lung Transplant
. 2024 Nov;
PMID: 39571635
Background: Surveillance bronchoscopies with bronchoalveolar lavage (BAL) and transbronchial biopsies (TBB) are primarily used to detect acute cellular rejection (ACR) or infection in lung transplant (LTx) recipients. We previously identified...
2.
Renaud-Picard B, Moshkelgosha S, Berra G, Cheung M, Hwang D, Hedley D, et al.
J Heart Lung Transplant
. 2024 Oct;
44(1):118-124.
PMID: 39368678
Long-term survival after lung transplantation remains limited by chronic lung allograft dysfunction (CLAD), with 2 main phenotypes: bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS). We aimed to assess...
3.
Miyamoto E, Vosoughi D, Wang J, Al-Refaee J, Berra G, Daigneault T, et al.
J Heart Lung Transplant
. 2024 Aug;
44(1):105-117.
PMID: 39097215
Background: Donor human leukocyte antigen (HLA)-specific antibodies (DSA) and non-HLA antibodies can cause allograft injury, possibly leading to chronic lung allograft dysfunction (CLAD) after lung transplantation. It remains unclear whether...
4.
Wilson G, Duong A, Moshkelgosha S, Bader G, Keshavjee S, Martinu T, et al.
Front Transplant
. 2024 Jul;
2:1161146.
PMID: 38993922
Background: Single-cell RNA-sequencing (scRNA-seq) technology has revealed novel cell populations in organs, uncovered regulatory relationships between genes, and allowed for tracking of cell lineage trajectory during development. It demonstrates promise...
5.
A Rapid Human Lung Tissue Dissociation Protocol Maximizing Cell Yield and Minimizing Cellular Stress
Duong A, Wong A, Ramendra R, Sebben D, Moshkelgosha S, MacParland S, et al.
Am J Respir Cell Mol Biol
. 2024 Jul;
71(5):509-518.
PMID: 38959415
The human lung is a complex organ that comprises diverse populations of epithelial, mesenchymal, vascular, and immune cells, which gains even greater complexity during disease states. To effectively study the...
6.
Beber S, Moshkelgosha S, White M, Zehong G, Cheung M, Hedley D, et al.
J Heart Lung Transplant
. 2024 Jun;
43(10):1654-1664.
PMID: 38852935
Background: T cells drive acute cellular rejection (ACR) and its progression to chronic lung allograft dysfunction (CLAD) following lung transplantation. International Society for Heart and Lung Transplantation grade A1 ACR...
7.
Bei K, Moshkelgosha S, Liu B, Juvet S
Front Immunol
. 2023 Dec;
14:1291649.
PMID: 38077395
Replacement of diseased organs with transplanted healthy donor ones remains the best and often only treatment option for end-stage organ disease. Immunosuppressants have decreased the incidence of acute rejection, but...
8.
Sadozai H, Rojas-Luengas V, Farrokhi K, Moshkelgosha S, Guo Q, He W, et al.
Clin Exp Immunol
. 2023 Apr;
213(1):138-154.
PMID: 37004176
The ability to induce tolerance would be a major advance in the field of solid organ transplantation. Here, we investigated whether autologous (congenic) hematopoietic stem cell transplantation (HSCT) could promote...
9.
Levy L, Moshkelgosha S, Huszti E, Hunter S, Renaud-Picard B, Berra G, et al.
J Heart Lung Transplant
. 2023 Mar;
42(8):1152-1160.
PMID: 36963446
Background: Airway epithelial injury is thought to be a key event in the pathogenesis of chronic lung allograft dysfunction (CLAD). We investigated whether markers of epithelial activity and injury in...
10.
Haykal S, Barone N, Rostami S, Moshkelgosha S, Juvet S, Keshavjee S, et al.
Plast Reconstr Surg Glob Open
. 2023 Mar;
11(3):e4831.
PMID: 36875922
Methods: Biopsies from vascularized composite transplant patients were obtained at scheduled visits and whenever skin changes occurred. Histology and immunohistochemistry were performed on all samples, looking at infiltrating cells. Results:...