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Saima G Anjum

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Citations 63
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Recent Articles
1.
Anjum S, Xu W, Nikkholgh N, Basu S, Nie Y, Thomas M, et al.
Genetics . 2013 Oct; 195(4):1307-17. PMID: 24077307
The Toll signaling pathway has a highly conserved function in innate immunity and is regulated by multiple factors that fine tune its activity. One such factor is β-arrestin Kurtz (Krz),...
2.
Nalam M, Ali A, Reddy G, Cao H, Anjum S, Altman M, et al.
Chem Biol . 2013 Sep; 20(9):1116-24. PMID: 24012370
The rapid evolution of HIV under selective drug pressure has led to multidrug resistant (MDR) strains that evade standard therapies. We designed highly potent HIV-1 protease inhibitors (PIs) using the...
3.
Jorissen R, Reddy G, Ali A, Altman M, Chellappan S, Anjum S, et al.
J Med Chem . 2009 Feb; 52(3):737-54. PMID: 19193159
We explore the applicability of an additive treatment of substituent effects to the analysis and design of HIV protease inhibitors. Affinity data for a set of inhibitors with a common...