Saige K Power
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Explore the profile of Saige K Power including associated specialties, affiliations and a list of published articles.
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5
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39
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Recent Articles
1.
Power S, Venkatesan S, Qu S, McLaurin J, Lambe E
Transl Neurodegener
. 2024 Dec;
13(1):58.
PMID: 39623428
Background: Cognitive reserve allows for resilience to neuropathology, potentially through active compensation. Here, we examine ex vivo electrophysiological evidence for active compensation in Alzheimer's disease (AD) focusing on the cholinergic...
2.
Xanomeline restores endogenous nicotinic acetylcholine receptor signaling in mouse prefrontal cortex
Power S, Venkatesan S, Lambe E
Neuropsychopharmacology
. 2023 Jan;
48(4):671-682.
PMID: 36635596
Cholinergic synapses in prefrontal cortex are vital for attention, but this modulatory system undergoes substantial pre- and post-synaptic alterations during adulthood. To examine the integrated impact of these changes, we...
3.
Venkatesan S, Jeoung H, Chen T, Power S, Liu Y, Lambe E
Curr Top Behav Neurosci
. 2020 Jul;
45:47-69.
PMID: 32601996
Acetylcholine regulates the cerebral cortex to sharpen sensory perception and enhance attentional focus. The cellular and circuit mechanisms of this cholinergic modulation are under active investigation in sensory and prefrontal...
4.
Oliver D, Intson K, Sargin D, Power S, McNabb J, Ramsey A, et al.
Neuropharmacology
. 2020 Feb;
168:108015.
PMID: 32092443
Social isolation raises the risk for mood disorders associated with serotonergic disruption. Yet, the underlying mechanisms by which the stress of social isolation increases risk are not well understood. Men...
5.
Sargin D, Chottekalapanda R, Perit K, Yao V, Chu D, Sparks D, et al.
Mol Psychiatry
. 2019 Aug;
25(5):1112-1129.
PMID: 31431686
In mood disorders, psychomotor and sensory abnormalities are prevalent, disabling, and intertwined with emotional and cognitive symptoms. Corticostriatal neurons in motor and somatosensory cortex are implicated in these symptoms, yet...