Saien Lu
Overview
Explore the profile of Saien Lu including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
143
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0
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Recent Articles
1.
He C, Lu S, Yu H, Sun Y, Zhang X
BMC Med
. 2025 Feb;
23(1):74.
PMID: 39915840
Background: High systolic blood pressure (HSBP) can cause adverse cardiovascular events and is therefore associated with a heavy global disease burden. However, this disease burden is poorly understood in youth...
2.
Han Y, Li Y, Wu Z, Pei Y, Lu S, Yu H, et al.
Ann Med
. 2024 Sep;
56(1):2405080.
PMID: 39301864
Background: Hypertension, a worldwide cardiovascular issue, is known to result in significant damage to the left ventricle. Left ventricular hypertrophy refers to an increase in ventricular mass, which is not...
3.
Zhang X, He C, Lu S, Yu H, Li G, Zhang P, et al.
J Clin Hypertens (Greenwich)
. 2024 Feb;
26(3):274-285.
PMID: 38341620
Electrocardiography (ECG) is an accessible diagnostic tool for screening patients with hypertensive left ventricular hypertrophy (LVH). However, its diagnostic sensitivity is low, with a high probability of false-negatives. Thus, this...
4.
Yin Z, You S, Zhang S, Zhang L, Wu B, Huang X, et al.
Biomed Pharmacother
. 2023 Aug;
166:115228.
PMID: 37557013
As a widely used lipid-lowering drug in clinical practice, atorvastatin is widely recognized for its role in protecting vascular endothelium in the cardiovascular system. However, a clear mechanistic understanding of...
5.
Zhang N, Zhang Y, Xu J, Wang P, Wu B, Lu S, et al.
Cell Res
. 2023 Jul;
33(9):679-698.
PMID: 37443257
The sarcomeric interaction of α-myosin heavy chain (α-MHC) with Titin is vital for cardiac structure and contraction. However, the mechanism regulating this interaction in normal and failing hearts remains unknown....
6.
Zhang N, Zhang Y, Chen Y, Qian H, Wu B, Lu S, et al.
Cell Discov
. 2023 May;
9(1):46.
PMID: 37156792
No abstract available.
7.
Zhang Y, Zhang N, Zou Y, Song C, Cao K, Wu B, et al.
Circ Res
. 2023 Feb;
132(5):601-624.
PMID: 36786216
Background: Hypertension can lead to podocyte damage and subsequent apoptosis, eventually resulting in glomerulosclerosis. Although alleviating podocyte apoptosis has clinical significance for the treatment of hypertensive nephropathy, an effective therapeutic...
8.
Lu X, Huang X, Xu H, Lu S, You S, Xu J, et al.
Cell Death Discov
. 2022 Oct;
8(1):421.
PMID: 36257929
Acute lymphoblastic leukemia (ALL) has been a huge threat for people's health and finding effective target therapy is urgent and important. WWP2, as one of E3 ubiquitin ligase, is involved...
9.
Lu X, Xu H, Xu J, Lu S, You S, Huang X, et al.
Front Physiol
. 2022 Sep;
13:968927.
PMID: 36091384
E3 ubiquitin ligases, an important part of ubiquitin proteasome system, catalyze the covalent binding of ubiquitin to target substrates, which plays a role in protein ubiquitination and regulates different biological...
10.
Zhang N, Zhang Y, Miao W, Shi C, Chen Z, Wu B, et al.
Redox Biol
. 2022 Jan;
50:102238.
PMID: 35066290
Oxidative stress-associated endothelial damage is the initiation factor of cardiovascular disease, and protein posttranslational modifications play critical roles in this process. Bcl-2-associated athanogene 3 (BAG3) is a molecular chaperone regulator...