Sai Kiang Lim
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Explore the profile of Sai Kiang Lim including associated specialties, affiliations and a list of published articles.
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109
Citations
15868
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Recent Articles
1.
Chandran N, Bhupendrabhai M, Tan T, Zhang B, Lim S, Choo A, et al.
Cytotherapy
. 2025 Feb;
PMID: 39918488
Background: Topical application of mesenchymal stem/stromal cell (MSC) exosomes have yielded encouraging results in the treatment of psoriasis in pre-clinical studies. The safety of topical applications of MSC exosome in...
2.
Tan T, Lim S
RNA Biol
. 2024 Dec;
22(1):1-7.
PMID: 39719370
Mesenchymal Stromal/Stem Cells (MSCs) are among the most frequently studied cell types in clinical trials, and their small extracellular vesicles (sEVs) are now being extensively investigated for therapeutic applications. The...
3.
Tan T, Lai R, Sim W, Zhang B, Lim S
Cytotherapy
. 2024 Aug;
27(1):1-6.
PMID: 39177523
Mesenchymal stem/stromal cells (MSC) have displayed promising therapeutic potential. Nonetheless, no United States Food and Drug Administration (FDA)-approved MSC product exists due largely to the absence of a reliable potency...
4.
Paolini L, Monguio-Tortajada M, Costa M, Antenucci F, Barilani M, Clos-Sansalvador M, et al.
J Extracell Biol
. 2024 Jun;
1(10):e63.
PMID: 38939213
Extracellular vesicles (EVs) large-scale production is a crucial point for the translation of EVs from discovery to application of EV-based products. In October 2021, the International Society for Extracellular Vesicles...
5.
Zhang B, Lai R, Sim W, Tan T, Lim S
Biomolecules
. 2024 Jun;
14(6).
PMID: 38927026
Mesenchymal stem/stromal cell-derived small extracellular vesicles (MSC-sEVs) are promising therapeutic agents. In this study, we investigated how the administration route of MSC-sEVs affects their therapeutic efficacy in a mouse model...
6.
Nguyen V, Welsh J, Tertel T, Choo A, van de Wakker S, Defourny K, et al.
J Extracell Vesicles
. 2024 Jun;
13(6):e12463.
PMID: 38868945
Mesenchymal stromal cells (MSCs) are promising regenerative therapeutics that primarily exert their effects through secreted extracellular vesicles (EVs). These EVs - being small and non-living - are easier to handle...
7.
Lam W, Zhuo W, Yang L, Tan R, Lim S, Hey H, et al.
Cells
. 2024 May;
13(9.
PMID: 38727297
Spinal fusion, a common surgery performed for degenerative lumbar conditions, often uses recombinant human bone morphogenetic protein 2 (rhBMP-2) that is associated with adverse effects. Mesenchymal stromal/stem cells (MSCs) and...
8.
Yang C, Lai R, Phua V, Aw S, Zhang B, Sim W, et al.
Int J Mol Sci
. 2024 Apr;
25(7).
PMID: 38612553
Mesenchymal stem/stromal cells (MSCs) are an extensively studied cell type in clinical trials due to their easy availability, substantial ex vivo proliferative capacity, and therapeutic efficacy in numerous pre-clinical animal...
9.
Poh B, Liew L, Soh Y, Lai R, Lim S, Ho Y, et al.
Stem Cells
. 2024 Feb;
42(5):416-429.
PMID: 38381602
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, accounting for 31% of all deaths globally. Myocardial ischemia-reperfusion injury (IRI), a common complication of CVDs, is a major cause...
10.
Welsh J, Goberdhan D, ODriscoll L, Buzas E, Blenkiron C, Bussolati B, et al.
J Extracell Vesicles
. 2024 Feb;
13(2):e12404.
PMID: 38326288
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker...