Sagar Vyavahare
Overview
Explore the profile of Sagar Vyavahare including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
69
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Recent Articles
1.
Gharpure M, Vyavahare S, Asante D, Chen J, Zhong R, Cooley M, et al.
Geroscience
. 2025 Jan;
PMID: 39875754
Alzheimer's disease (AD), a progressive neurodegenerative disorder, is frequently associated with musculoskeletal complications, including sarcopenia and osteoporosis, which substantially impair patient quality of life. Despite these clinical observations, the molecular...
2.
Manfredi J, Gupta S, Vyavahare S, Deak F, Lu X, Buddha L, et al.
Physiol Behav
. 2024 Dec;
290:114778.
PMID: 39672482
Alzheimer's Disease (AD) is a debilitating neurocognitive disorder with an unclear underlying mechanism. Recent studies have implicated gut microbiota dysbiosis with the onset and progression of AD. The connection between...
3.
Fernicola J, Vyavahare S, Gupta S, Kalwaghe A, Kosmac K, Davis A, et al.
Int J Mol Sci
. 2024 Jul;
25(14).
PMID: 39062842
Muscle wasting can be caused by nutrition deficiency and inefficient metabolism of amino acids, including Branched Chain Amino Acids (BCAAs). Branched Chain Amino Acids are a major contributor to the...
4.
Patel S, Badruzzaman Khan M, Kumar S, Vyavahare S, Mendhe B, Lee T, et al.
Exp Neurol
. 2024 Jun;
379:114867.
PMID: 38914274
An ischemic stroke (IS) is caused due to the lack of blood flow to cerebral tissue. Most of the studies have focused on how stroke affects the localized tissue, but...
5.
Vyavahare S, Ahluwalia P, Gupta S, Kolhe R, Hill W, Hamrick M, et al.
Int J Tryptophan Res
. 2024 May;
17:11786469241246674.
PMID: 38757095
Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, is crucial in maintaining the skeletal system. Our study focuses on encapsulating the role of AhR in bone biology and identifying novel...
6.
Alterations in Alzheimer's disease microglia transcriptome might be involved in bone pathophysiology
Gharpure M, Vyavahare S, Ahluwalia P, Gupta S, Lee T, Lohakare J, et al.
Neurobiol Dis
. 2024 Jan;
191:106404.
PMID: 38184014
Aging is a major risk factor for multiple chronic disorders in the elderly population, including Alzheimer's disease (AD) and Osteoporosis. AD is a progressive neurodegenerative disease characterized by memory loss....
7.
Gupta S, Vyavahare S, Duchesne Blanes I, Berger F, Isales C, Fulzele S
Exp Gerontol
. 2023 Oct;
183:112319.
PMID: 37898179
The intricate interplay between gut microbiota and the host is pivotal in maintaining homeostasis and health. Dietary tryptophan (TRP) metabolism initiates a cascade of essential endogenous metabolites, including kynurenine, kynurenic...
8.
Vyavahare S, Kumar S, Smith K, Mendhe B, Zhong R, Cooley M, et al.
Aging Dis
. 2023 May;
14(6):2303-2316.
PMID: 37199586
Emerging evidence shows that the microRNA-141-3p is involved in various age-related pathologies. Previously, our group and others reported elevated levels of miR-141-3p in several tissues and organs with age. Here,...
9.
Gharpure M, Chen J, Nerella R, Vyavahare S, Kumar S, Isales C, et al.
Geroscience
. 2023 Apr;
45(3):1303-1316.
PMID: 37106281
Sarcopenia is a medical condition that progressively develops with age and results in reduced skeletal muscle mass, alteration in muscle composition, and decreased muscle strength. Several clinical studies suggested that...
10.
Muller P, Lee T, Zhi W, Kumar S, Vyavahare S, Sharma A, et al.
Life (Basel)
. 2023 Mar;
13(3).
PMID: 36983761
Osteoarthritis (OA) is a highly prevalent degenerative joint condition that disproportionately affects females. The pathophysiology of the disease is not well understood, which makes diagnosis and treatment difficult. Given the...