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Sabrina Valetti

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Articles 21
Citations 204
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Recent Articles
1.
Hernandez A, Bogdanova E, Campos Pacheco J, Kocherbitov V, Ekstrom M, Pilkington G, et al.
Drug Deliv . 2024 Jul; 31(1):2381340. PMID: 39041383
Pulmonary delivery and formulation of biologics are among the more complex and growing scientific topics in drug delivery. We herein developed a dry powder formulation using disordered mesoporous silica particles...
2.
van der Zwaan I, Pilkington G, Frenning G, Ekstrom M, Valetti S, Pitcairn G, et al.
Eur J Pharm Sci . 2024 Jun; 200:106828. PMID: 38862047
The potential of micron-sized amorphous mesoporous silica particles as a novel controlled release drug delivery system for pulmonary administration has been investigated. Mesoporous silica formulations were demonstrated to provide a...
3.
Campos Pacheco J, Yalovenko T, Riaz A, Kotov N, Davids C, Persson A, et al.
J Control Release . 2024 Mar; 369:231-250. PMID: 38479444
Inhalation therapy treating severe infectious disease is among the more complex and emerging topics in controlled drug release. Micron-sized carriers are needed to deposit drugs into the lower airways, while...
4.
Riaz A, Gidvall S, Prgomet Z, Hernandez A, Ruzgas T, Nilsson E, et al.
Pharmaceutics . 2023 May; 15(5). PMID: 37242755
Oral transmucosal administration, where drugs are absorbed directly through the non-keratinized, lining mucosa of the mouth, represents a solution to drug delivery with several advantages. Oral mucosal equivalents (OME) developed...
5.
Valetti S, Riaz A, Doko A, Sultana K, Eskandari M, Prgomet Z, et al.
Int J Pharm . 2022 Sep; 627:122222. PMID: 36155795
Migraine is a highly prevalent neurological disease affecting circa 1 billion patients worldwide with severe incapacitating symptoms, which significantly diminishes the quality of life. As self-medication practice, oral administration of...
6.
Gidvall S, Bjorklund S, Feiler A, Dahlstrom B, Ronn R, Engblom J, et al.
Eur J Pharm Sci . 2021 Aug; 166:105983. PMID: 34461276
Oral transmucosal drug delivery is a non-invasive administration route for rapid therapeutic onset and greater bioavailability avoiding the first-pass metabolism. Mucoadhesive formulations are advantageous as they may retain the drug...
7.
Valetti S, Thomsen H, Wankar J, Falkman P, Manet I, Feiler A, et al.
Int J Pharm . 2021 Apr; 602:120609. PMID: 33901597
When applied to skin, particulate matter has been shown to accumulate in hair follicles. In addition to follicles, the skin topography also incorporates trench-like furrows where particles potentially can accumulate;...
8.
Valetti S, Wankar J, Ericson M, Feiler A, Manet I
J Mater Chem B . 2020 Apr; 5(17):3201-3211. PMID: 32263718
Three types of new label-free fluorescent mesoporous silica micro- and nanoparticles were prepared by controlled thermal decomposition of carboamino groups linked on the surface without compromising the drug loading capacity...
9.
Angiolini L, Valetti S, Cohen B, Feiler A, Douhal A
Phys Chem Chem Phys . 2018 Apr; 20(17):11899-11911. PMID: 29666860
We report on the encapsulation of the antibiotic clofazimine (CLZ) within the pores of mesoporous silica particles having hydrophilic (CBET value of 137) and more hydrophobic (CBET value of 94...
10.
Afonso D, Valetti S, Fraix A, Bascetta C, Petralia S, Conoci S, et al.
Nanoscale . 2017 Aug; 9(36):13404-13408. PMID: 28813066
Amino-terminated mesoporous silica nanoparticles embedding carbon dots (MSCD) formed by calcination were functionalized with a nitric oxide (NO) photodonor (1) to give a robust MSCD-1 conjugate. The intense fluorescence of...