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Sabine Ring

Explore the profile of Sabine Ring including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 1391
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Recent Articles
1.
Da M, Chen L, Enk A, Ring S, Mahnke K
Front Immunol . 2022 Jun; 13:914799. PMID: 35711418
Adenosine (Ado) has been shown to have immunosuppressive effects in a variety of diseases. It can either be released directly into the extracellular environment by cells, or it can be...
2.
Ring S, Inaba Y, Da M, Bopp T, Grabbe S, Enk A, et al.
J Invest Dermatol . 2021 Mar; 141(8):2006-2017. PMID: 33675787
The healing phase of contact hypersensitivity reactions is critically dependent on regulatory T cells (Tregs), but even the early inflammatory phase, that is, 6-24 hours after induction of a contact...
3.
Silva-Vilches C, Ring S, Mahnke K
Front Immunol . 2018 Nov; 9:2581. PMID: 30473700
Adenosine (Ado) is a well-studied neurotransmitter, but it also exerts profound immune regulatory functions. Ado can (i) actively be released by various cells into the tissue environment and can (ii)...
4.
Silva-Vilches C, Ring S, Schrader J, Clausen B, Probst H, Melchior F, et al.
J Invest Dermatol . 2018 Nov; 139(3):541-551. PMID: 30393085
Dendritic cells (DCs) express the ecto-5'-nucleotidase CD73 that generates immunosuppressive adenosine (Ado) by dephosphorylation of extracellular Ado monophosphate and diphosphate. To investigate whether CD73-derived Ado has immune-suppressive activity, 2,4-dinitrothiocyanobenzene (DNTB)...
5.
Schneider T, Hoffmann H, Dienemann H, Herpel E, Heussel C, Enk A, et al.
Semin Thorac Cardiovasc Surg . 2017 Jan; 28(2):585-592. PMID: 28043482
The objective includes radiofrequency ablation (RFA) of a cancerous nodule results in immunogenic cell death. Tumor antigens are presented and the inflammatory environment may help stimulate adaptive and innate antitumor...
6.
Mahnke K, Useliene J, Ring S, Kage P, Jendrossek V, Robson S, et al.
J Invest Dermatol . 2016 Sep; 137(1):106-114. PMID: 27623510
Injection of regulatory T cells (Tregs) followed by sensitization with 2,4,6-trinitrochlorobenzene induced a transient increase in size and cellularity of skin-draining lymph nodes (LNs) in mice. This led us to...
7.
Mahnke K, Ring S, Enk A
Front Immunol . 2016 Mar; 7:63. PMID: 26941742
Dendritic cells (DCs) are often defined as pivotal inducers of immunity, but these proinflammatory properties only develop after stimulation or ex vivo manipulation of DCs. Under non-inflammatory conditions in vivo,...
8.
Ring S, Pushkarevskaya A, Schild H, Probst H, Jendrossek V, Wirsdorfer F, et al.
J Immunol . 2015 Mar; 194(8):3735-44. PMID: 25780038
Dendritic cells (DC) are one target for immune suppression by regulatory T cells (Treg), because their interaction results in reduced T cell stimulatory capacity and secretion of inhibitory cytokines in...
9.
Ring S, Maas M, Nettelbeck D, Enk A, Mahnke K
J Immunol . 2013 Aug; 191(6):2938-47. PMID: 23945139
The dendritic and epithelial cell receptor with a m.w. of 205 kDa (DEC205) is expressed by dendritic cells (DCs) and facilitates Ag presentation. After injection of Ags coupled to Abs...
10.
Fujimura T, Ring S, Umansky V, Mahnke K, Enk A
J Invest Dermatol . 2011 Dec; 132(4):1239-46. PMID: 22189788
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells, and they promote an immunosuppressive environment in tumor-bearing hosts. To characterize MDSCs in melanoma, we examined the expression of inhibitory...