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Sabine Grosser

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Articles 13
Citations 157
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Recent Articles
1.
Ishihara Y, Sato F, Guinet A, Grosser S, Vida I, Kubota Y, et al.
Neuroscience . 2025 Jan; 568:285-297. PMID: 39755232
The subiculum is the main output part of the hippocampal formation and is important for learning and memory. According to connection studies, the distal and proximal regions of the subiculum...
2.
Mittermaier F, Kalbhenn T, Xu R, Onken J, Faust K, Sauvigny T, et al.
Nat Commun . 2024 Dec; 15(1):10340. PMID: 39668146
Synaptic mechanisms that contribute to human memory consolidation remain largely unexplored. Consolidation critically relies on sleep. During slow wave sleep, neurons exhibit characteristic membrane potential oscillations known as UP and...
3.
Guinet A, Grosser S, Ozbay D, Behr J, Vida I
Front Cell Neurosci . 2024 May; 18:1368627. PMID: 38716238
The balance between excitation and inhibition is essential to the proper function of cortical circuits. To maintain this balance during dynamic network activity, modulation of the strength of inhibitory synapses...
4.
Peng Y, Bjelde A, Vilimelis Aceituno P, Mittermaier F, Planert H, Grosser S, et al.
Science . 2024 Apr; 384(6693):338-343. PMID: 38635709
The computational capabilities of neuronal networks are fundamentally constrained by their specific connectivity. Previous studies of cortical connectivity have mostly been carried out in rodents; whether the principles established therein...
5.
Scheuer T, Brinke E, Grosser S, Wolf S, Mattei D, Sharkovska Y, et al.
Development . 2021 Sep; 148(20). PMID: 34557899
The inhibitory GABAergic system in the brain is involved in the etiology of various psychiatric problems, including autism spectrum disorders (ASD), attention deficit hyperactivity disorder (ADHD) and others. These disorders...
6.
Grosser S, Barreda F, Beed P, Schmitz D, Booker S, Vida I
eNeuro . 2021 Feb; 8(1). PMID: 33531369
The medial entorhinal cortex (mEC) shows a high degree of spatial tuning, predominantly grid cell activity, which is reliant on robust, dynamic inhibition provided by local interneurons (INs). In fact,...
7.
Grosser S, Buck N, Braunewell K, Gilling K, Wozny C, Fidzinski P, et al.
Front Mol Neurosci . 2020 Sep; 13:143. PMID: 32982687
Patients suffering from temporal lobe epilepsy (TLE) show severe problems in hippocampus dependent memory consolidation. Memory consolidation strongly depends on an intact dialog between the hippocampus and neocortical structures. Deficits...
8.
Bolduan F, Grosser S, Vida I
Brain Struct Funct . 2020 Sep; 225(8):2577-2589. PMID: 32918613
The morphological structure of neurons provides the basis for their functions and is a major focus of contemporary neuroscience studies. Intracellular staining of single cells in acute slices is a...
9.
Janach G, Reetz O, Dohne N, Stadler K, Grosser S, Byvaltcev E, et al.
J Neuroinflammation . 2020 Feb; 17(1):69. PMID: 32087716
Background: Interferon-γ (IFN-γ, a type II IFN) is present in the central nervous system (CNS) under various conditions. Evidence is emerging that, in addition to its immunological role, IFN-γ modulates...
10.
Lehnhoff J, Strauss U, Wierschke S, Grosser S, Pollali E, Schneider U, et al.
Neuropharmacology . 2018 Oct; 144:58-69. PMID: 30315843
Alterations of the hyperpolarization activated nonselective cation current (I) are associated with epileptogenesis. Accordingly, the second-generation antiepileptic drug lamotrigine (LTG) enhances I in rodent hippocampus. We directly evaluated here whether...