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Sabine Blouquit-Laye

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Articles 18
Citations 389
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Recent Articles
1.
Marougka K, Judith D, Jaouen T, Blouquit-Laye S, Cosentino G, Berlioz-Torrent C, et al.
PLoS Pathog . 2024 Nov; 20(11):e1012687. PMID: 39561185
Human respiratory syncytial virus (RSV) is an enveloped RNA virus and the leading viral agent responsible for severe pediatric respiratory infections worldwide. Identification of cellular factors able to restrict viral...
2.
Le Moigne V, Blouquit-Laye S, Desquesnes A, Girard-Misguich F, Herrmann J
J Antimicrob Chemother . 2022 Oct; 77(12):3496-3503. PMID: 36253948
Background: Mycobacterium abscessus (Mabs), a rapidly growing Mycobacterium species, is considered an MDR organism. Among the standard antimicrobial multi-drug regimens against Mabs, amikacin is considered as one of the most...
3.
Bouillier C, Cosentino G, Leger T, Rincheval V, Richard C, Desquesnes A, et al.
Sci Rep . 2019 Oct; 9(1):15258. PMID: 31649314
Human respiratory syncytial virus (RSV) is a globally prevalent negative-stranded RNA virus, which can cause life-threatening respiratory infections in young children, elderly people and immunocompromised patients. Its transcription termination factor...
4.
Bouillier C, Rincheval V, Sitterlin D, Blouquit-Laye S, Desquesnes A, Eleouet J, et al.
J Vis Exp . 2019 Apr; (146). PMID: 31009004
The use of recombinant viruses has become crucial in basic or applied virology. Reverse genetics has been proven to be an extremely powerful technology, both to decipher viral replication mechanisms...
5.
Tchoukaev A, Taytard J, Rousselet N, Rebeyrol C, Debray D, Blouquit-Laye S, et al.
Front Pharmacol . 2018 Jun; 9:545. PMID: 29922157
Cystic fibrosis (CF) is characterized by a chronic pulmonary inflammation. In CF, glucocorticoids (GC) are widely used, but their efficacy and benefit/risk ratio are still debated. In plasma, corticosteroid-binding globulin...
6.
Bardin P, Marchal-Duval E, Sonneville F, Blouquit-Laye S, Rousselet N, Le Rouzic P, et al.
J Pathol . 2018 May; 245(4):410-420. PMID: 29732561
Cystic fibrosis (CF) is the most common lethal genetic disease, caused by CFTR (cystic fibrosis transmembrane conductance regulator) gene mutations. CF is characterized by an ionic imbalance and thickened mucus,...
7.
Sonneville F, Ruffin M, Coraux C, Rousselet N, Le Rouzic P, Blouquit-Laye S, et al.
Nat Commun . 2017 Sep; 8(1):710. PMID: 28955034
Cystic fibrosis results from reduced cystic fibrosis transmembrane conductance regulator protein activity leading to defective epithelial ion transport. Ca-activated Cl channels mediate physiological functions independently of cystic fibrosis transmembrane conductance...
8.
Rincheval V, Lelek M, Gault E, Bouillier C, Sitterlin D, Blouquit-Laye S, et al.
Nat Commun . 2017 Sep; 8(1):563. PMID: 28916773
Infection of cells by respiratory syncytial virus induces the formation of cytoplasmic inclusion bodies (IBs) where all the components of the viral RNA polymerase complex are concentrated. However, the exact...
9.
Faisy C, Grassin-Delyle S, Blouquit-Laye S, Brollo M, Naline E, Chapelier A, et al.
PLoS One . 2014 Nov; 9(10):e111350. PMID: 25360795
Background: Regular use of β2-agonists may enhance non-specific airway responsiveness. The wingless/integrated (Wnt) signaling pathways are responsible for several cellular processes, including airway inflammation and remodeling while cAMP-PKA cascade can...
10.
Ruffin M, Voland M, Marie S, Bonora M, Blanchard E, Blouquit-Laye S, et al.
Biochim Biophys Acta . 2013 Oct; 1832(12):2340-51. PMID: 24080196
Cystic fibrosis (CF) airway epithelium is constantly subjected to injury events due to chronic infection and inflammation. Moreover, abnormalities in CF airway epithelium repair have been described and contribute to...