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Saba Sheikh

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Articles 25
Citations 347
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Recent Articles
1.
Sheikh S, Stefanovski D, Kilberg M, Hadjiliadis D, Rubenstein R, Rickels M, et al.
Front Endocrinol (Lausanne) . 2024 Mar; 15:1340346. PMID: 38444582
Methods: Secondary data analysis of CF-focused prospective studies was performed in PwCF categorized as 1) pancreatic insufficient [PI-CF] or 2) pancreatic sufficient [PS-CF] and in 3) non-CF controls. MMTT: insulin...
2.
Flatt A, Sheikh S, Peleckis A, Alvarado P, Hadjiliadis D, Stefanovski D, et al.
J Clin Endocrinol Metab . 2023 Jul; 109(1):151-160. PMID: 37503734
Context: Elexacaftor/tezacaftor/ivacaftor (ETI; Trikafta) enhances aberrant cystic fibrosis transmembrane conductance regulator function and may improve the insulin secretory defects associated with a deterioration in clinical outcomes in pancreatic insufficient cystic...
3.
Lei W, Kilberg M, Zemel B, Rubenstein R, Harris C, Sheikh S, et al.
J Clin Transl Endocrinol . 2022 Sep; 30:100304. PMID: 36110921
Background: Gut-derived incretin hormones, including glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide 1 (GLP-1), regulate post-prandial glucose metabolism by promoting insulin production. GIP, GLP-1, and insulin contribute to the acute...
4.
Nyirjesy S, Peleckis A, Eiel J, Gallagher K, Doliba A, Tami A, et al.
Diabetes . 2022 Jul; 71(10):2153-2165. PMID: 35796669
Impaired insulin and incretin secretion underlie abnormal glucose tolerance (AGT) in pancreatic insufficient cystic fibrosis (PI-CF). Whether the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) can enhance...
5.
Bass R, Tindall A, Sheikh S
Nutrients . 2022 Feb; 14(4). PMID: 35215485
(1) Background: Malnutrition has been a hallmark of cystic fibrosis (CF) for some time, and improved nutritional status is associated with improved outcomes. While individuals with CF historically required higher...
6.
Zysman-Colman Z, Munsar Z, Sheikh S, Rubenstein R, Kelly A
J Pediatr . 2021 Dec; 243:116-121.e3. PMID: 34871592
Objectives: To compare performance of weight-for-length and body mass index as estimators of undernutrition in children with cystic fibrosis (CF). Study Design: We analyzed pediatric anthropometric data from the Cystic...
7.
Kelly A, Sheikh S, Stefanovski D, Peleckis A, Nyirjesy S, Eiel J, et al.
J Clin Endocrinol Metab . 2021 Nov; 107(4):e1778. PMID: 34792139
No abstract available.
8.
Kelly A, Sheikh S, Stefanovski D, Peleckis A, Nyirjesy S, Eiel J, et al.
J Clin Endocrinol Metab . 2021 Aug; 106(9):2617-2634. PMID: 34406395
Purpose: Impaired incretin secretion may contribute to the defective insulin secretion and abnormal glucose tolerance (AGT) that associate with worse clinical outcomes in pancreatic insufficient cystic fibrosis (PI-CF). The study...
9.
Kilberg M, Harris C, Sheikh S, Stefanovski D, Cuchel M, Kubrak C, et al.
J Clin Endocrinol Metab . 2020 Jul; 105(10). PMID: 32668452
Context: Oral glucose tolerance test (OGTT)-related hypoglycemia is common in pancreatic-insufficient cystic fibrosis (PI-CF), but its mechanistic underpinnings are yet to be established. Objective: To delineate the mechanism(s) underlying OGTT-related...
10.
Zysman-Colman Z, Kilberg M, Harrison V, Chesi A, Grant S, Mitchell J, et al.
Pediatr Res . 2020 May; 89(3):653-659. PMID: 32386398
Background: Despite improved health, shorter stature is common in cystic fibrosis (CF). We aimed to describe height velocity (HV) and contribution of height-related genetic variants to height (HT) in CF....