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S Waller

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Articles 56
Citations 457
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Recent Articles
11.
Steward W, Middleton M, Benghiat A, Loadman P, Hayward C, Waller S, et al.
Ann Oncol . 2007 Apr; 18(6):1098-103. PMID: 17442658
Background: AQ4N (1,4-bis[[2-(dimethylamino)ethyl] amino]-5,8-dihydroxyanthracene-9, 10-dione bis-N-oxide dihydrochloride) is a prodrug which is selectively activated within hypoxic tissues to AQ4, a topoisomerase II inhibitor and DNA intercalator. Patients And Methods: In...
12.
Jameson M, Baguley B, Kestell P, Zhao L, Paxton J, Thompson P, et al.
Cancer Chemother Pharmacol . 2006 Oct; 59(5):681-7. PMID: 17021822
Purpose: 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) (AS1404) is a novel antitumour agent that selectively disrupts tumour vasculature and induces cytokines. The purpose of this study was to determine the pharmacokinetics (PK) of...
13.
Waller S, Tremelling M, Bredin F, Godfrey L, Howson J, Parkes M
Gut . 2005 Dec; 55(6):809-14. PMID: 16361305
Background And Aims: Genetic association between Crohn's disease (CD) and OCTN1 (SLC22A4) C1672T/OCTN2 (SLC22A5) G-207C variants in IBD5 has recently been reported. These genes encode solute carriers and the association...
14.
Waterston A, Gumbrell L, Bratt T, Waller S, Gustav-Aspland J, Lhermenier C, et al.
Cancer Immunol Immunother . 2005 Mar; 54(9):848-57. PMID: 15754205
We evaluated the safety and immunogencity of a novel vaccine directed against autologous TNFalpha in a Phase I fixed dose escalation trial. The vaccine consisted of two recombinant TNFalpha proteins,...
15.
Kerckhove L, Waller S
J Value Inq . 2004 Aug; 32(2):175-89. PMID: 15295850
No abstract available.
16.
Rustin G, Bradley C, Galbraith S, Stratford M, Loadman P, Waller S, et al.
Br J Cancer . 2003 Apr; 88(8):1160-7. PMID: 12698178
The purpose of this phase I, dose-escalation study was to determine the toxicity, maximum tolerated dose, pharmacokinetics, and pharmacodynamic end points of 5,6-dimethylxanthenone acetic acid (DMXAA). In all, 46 patients...
17.
Davies J, Waller S, Zeng Q, Wells S, Murphy D
J Neuroendocrinol . 2003 Jan; 15(1):42-50. PMID: 12535168
We have introduced transgenes into rats with a view to defining genomic regions that mediate the cell-specific and physiological regulation of the vasopressin gene. These transgenes consist of the rat...
18.
Lipchik G, Holroyd K, ODONNELL F, Cordingley G, Waller S, Labus J, et al.
Cephalalgia . 2000 Dec; 20(7):638-46. PMID: 11128821
We examined pericranial muscle tenderness and abnormalities in the second exteroceptive suppression period (ES2) of the temporalis muscle in chronic tension-type headache (CTTH; n = 245) utilizing a blind design...
19.
Murphy D, Xu J, Waller S
Exp Physiol . 2000 May; 85 Spec No:211S-222S. PMID: 10795925
Over the past 10-15 years, profoundly important transgenic techniques have been developed that enable new genes to be introduced into whole mammalian organisms. This review describes the ways in which...
20.
Waller S
Nurs Times . 2000 Apr; 95(40):32-3. PMID: 10745837
No abstract available.